Evidence map›Paper›PMID 40124112›Full record

ReviewIBRO neuroscience reports2025

Advances in the molecular mechanisms of zinc-finger transcription factors in neurodevelopmental disorders.

Hailin Wang, Ying Yang, Ziwei Ni, Xiaoting Qiao, Yaqian Guo, Xiaomin Wang, Duo Cao, Yayun Wang, Cailian Ruan

Abstract readReview
In one paragraph

Review in IBRO neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. International journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hailin WangMedical School of Yan'an University, Yan'an, Shaanxi 716000, China.
Ying YangShaanxi Institute for Pediatric Diseases, Xi'an Children's Hospital, Xi'an, China.
Ziwei NiMedical School of Yan'an University, Yan'an, Shaanxi 716000, China.
Xiaoting QiaoMedical School of Yan'an University, Yan'an, Shaanxi 716000, China.
Yaqian GuoMedical School of Yan'an University, Yan'an, Shaanxi 716000, China.
Xiaomin WangMedical School of Yan'an University, Yan'an, Shaanxi 716000, China.
Duo CaoSchool of Life Sciences, Yan'an University, Yan'an, Shaanxi 716000, China.
Yayun WangNational Experimental Center of Air Force Medical University, Xi'an, Shaanxi 716000, China.
Cailian RuanMedical School of Yan'an University, Yan'an, Shaanxi 716000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurodevelopmental disorders (NDDs) constitute a heterogeneous group of early-onset brain dysfunction disorders, which may arise from genetic or acquired etiologies. These disorders are characterized by behavioral and cognitive deficits that predominantly manifest during childhood development, thereby potentially impairing an individual's performance in learning, sports, and social situations. A comprehensive understanding of the pathogenesis of NDDs is crucial for the development of targeted therapeutic interventions. Zinc-finger transcription factors (ZFPs) play a pivotal role in regulating gene expression by modulating the binding of RNA polymerase to DNA, thereby either activating or repressing gene transcription. In recent years, the

Indexed as

BCL11ABCL11BNeurodevelopmental disordersZinc-finger transcription factors

Identifiers

PMID40124112
PMCPMC11930196

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.