ArticleJournal of inflammation research2025
White Blood Cell Count Is Associated with Hyperuricemia in Patients with Type 2 Diabetes Mellitus.
Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and risk factors of hyperuricemia and gout in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Laboratory Biomarker Profiles and Phenotypic Discrimination in Coronary Artery Disease with Metabolic and Renal Comorbidities: A Cross-Sectional Study.International journal of general medicine · 2026Article
- Association between serum carcinoembryonic antigen levels and atherosclerotic cardiovascular disease in patients with type 2 diabetes mellitus.European journal of medical research · 2025Article
- Integrating convolutional neural networks with ensemble methods for enhanced diabetes diagnosis: a multi-dataset evaluation.Frontiers in medicine · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Hyperuricemia is highly prevalent among patients with type 2 diabetes mellitus (T2DM). Inflammation is associated with the process of hyperuricemia. However, it is unclear whether white blood cell (WBC) count, a convenient inflammatory marker, is associated with hyperuricemia in patients with T2DM. Thus, we aimed to explore the possible association between WBC count and hyperuricemia in patients with T2DM. Methods: A total of 1768 patients with T2DM were retrospectively included. Cumulative data were analyzed in patients with T2DM. Results: WBC count was significantly elevated in T2DM patients with hyperuricemia compared with those without hyperuricemia (6.80 [5.60, 8.02] vs 6.20 [5.27, 7.24] 10 Conclusion: Elevated WBC count, even within the normal range, is associated with hyperuricemia in patients with T2DM, suggesting that chronic inflammation, as indicated by a higher WBC count, may be related to the development of hyperuricemia in patients with T2DM and urate-lowering therapy may be helpful to ameliorate chronic inflammatory damage in T2DM patients with hyperuricemia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.