Evidence mapPaperPMID 40126017Full record

ArticlemBio2025

Standard mouse diets lead to differences in severity in infectious and non-infectious colitis.

Joshua E Denny, Julia N Flores, Nontokozo V Mdluli, Michael C Abt

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Clostridioides difficile pathogenesis and control.Nature reviews. Microbiology · 2026
    Review
  3. The emerging view on the roles of butyrate inInfection and immunity · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joshua E DennyDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-2004-5030
Julia N FloresDivision of Infectious Disease, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Nontokozo V MdluliDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Michael C AbtDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-7351-2061

Funding

UNIVERSITY OF PENNSYLVANIA CAN CTR SUPPORT GRANTP30CA016520 · NCI · UNIVERSITY OF PENNSYLVANIA · PI EDWARD J DELIKATNY · 1985 to 2026
$222.3M
Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Ronald G Collman · 1999 to 2026
$78.6M
TRANSGENIC AND CHIMERIC MOUSE COREP30DK050306 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI Ken Hashigiwa Cadwell · 1997 to 2026
$32.5M
Investigating Immune-Microbiome interactions during treatment of Clostridioides difficile with fecal microbiome transplantationR01AI158830 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ABT, MICHAEL C. · 2021 to 2025
$2.4M
Immune regulation of the transcriptional and spatial profile of Clostridioides difficileR21AI164385 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ABT, MICHAEL C. · 2021 to 2022
$447k
Crohn's and Colitis Foundation (CCF) 1005576HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI158830HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R21AI164385NCI NIH HHS P30 CA016520NIAID NIH HHS P30 AI045008NIAID NIH HHS R01 AI158830NIAID NIH HHS R21 AI164385NIDDK NIH HHS P30 DK050306
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Clostridioides difficileClostridium InfectionsColitisDietGastrointestinal MicrobiomeAnimalsDisease Models, AnimalFemaleMaleMiceMice, Inbred C57BLSeverity of Illness IndexClostridioides difficilecolitisdietgut inflammationgut microbiotametabolome

Identifiers

PMID40126017
PMCPMC11980566

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.