ReviewBioanalysis2025
Advances in green sample preparation methods for bioanalytical laboratories focusing on drug analysis.
Review in Bioanalysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Hydrophilicity-switchable deep eutectic solvent-based ultrasound-assisted liquid-phase microextraction for the green and efficient spectrofluorimetric determination of verapamil in human plasma.Scientific reports · 2026Article
- Exploiting a Microdisk Array Device for Enhanced Microextraction of Indomethacin from Human Urine.ACS omega · 2026Article
- Plant-Based Polysaccharide Gums as Sustainable Bio-Polymers: Focus on Tragacanth Gum and Its Emerging Applications.Polymers · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bioanalytical laboratories face significant challenges in sample preparation due to the complexity of biological matrices and the low concentrations of target analytes. This review focuses on advances in green sample preparation (GSP) techniques tailored to meet these challenges while promoting sustainability. Innovations in sorbents, including metal-organic frameworks (MOFs), magnetic nanoparticles (MNPs), sol-gel-based materials, molecularly imprinted polymers (MIPs), carbon-based materials, and natural sorbents like cellulose and kapok fiber, have enhanced extraction efficiency and selectivity. Green solvents such as deep eutectic solvents (DES), ionic liquids (ILs), supramolecular solvents (SUPRAs), and switchable hydrophilicity solvents (SHSs) further reduce environmental impact by minimizing toxic solvent use. This review highlights their use in drug analysis, emphasizing their roles in enhancing extraction efficiency, selectivity, and environmental sustainability. Recent applications demonstrate the integration of these sorbents and solvents into bioanalytical workflows, significantly improving analytical performance while adhering to Green Analytical Chemistry (GAC) principles. It is anticipated that this comprehensive review will aid scholars in the formulation of selective, rapid, environmentally friendly, straightforward, sensitive, and precise analytical methodologies for bioanalysis, thereby promoting innovation and sustainability within drug analysis protocols.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.