Evidence map›Paper›PMID 40127277›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Lysosomal PIP

Ayse Z Sahan, Mingyuan Chen, Qi Su, Qingrong Li, Dong Wang, Jin Zhang

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Subcellular Cartography of the Phosphoinositide Multiverse.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2026
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ayse Z Sahan *Department of Pharmacology, University of California, San Diego, CA 92093.ORCID 0000-0003-4661-035X
Mingyuan Chen *Department of Pharmacology, University of California, San Diego, CA 92093.
Qi SuDepartment of Pharmacology, University of California, San Diego, CA 92093.ORCID 0000-0002-7393-1696
Qingrong LiDivision of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, CA 92093.
Dong WangDivision of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, CA 92093.ORCID 0000-0002-2829-1546
Jin ZhangDepartment of Pharmacology, University of California, San Diego, CA 92093.ORCID 0000-0001-7145-7823

Funding

GRADUATE TRAINING IN CELLULAR &MOLECULAR PHARMACOLOGYT32GM007752 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROWN, JOAN HELLER, HANDEL, TRACY M · 1985 to 2023
$13.5M
Live-cell Activity Architecture in CancerR35CA197622 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jin Zhang · 2015 to 2026
$11.2M
Signal Transduction by PI3K/mTORR01DE030497 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GUTKIND, JORGE SILVIO, ZHANG, JIN · 2021 to 2025
$2.4M
Recognition of Synthetic Unnatural Base Pairs by RNA PolymeraseR01GM148476 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Dong Wang · 2023 to 2026
$1.6M
Spatial regulation of mechanistic target of rapamycin complex 1 (mTORC1) and its role in oral squamous cell carcinomaF31DE032886 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SAHAN, AYSE ZISAN · 2023 to 2024
$85k
HHS | NIH (NIH) 1F31DE032886HHS | NIH (NIH) CA197622HHS | NIH (NIH) DE030497HHS | NIH (NIH) GM007752HHS | NIH (NIH) GM148476NCI NIH HHS R35 CA197622NIDCR NIH HHS F31 DE032886NIDCR NIH HHS R01 DE030497NIGMS NIH HHS R01 GM148476NIGMS NIH HHS T32 GM007752
6 · The paper itself

Abstract

3-Phosphoinositides (3-PIs), phosphatidylinositol (3,4) bisphosphate [PI(3,4)P

Indexed as

Biosensing TechniquesLysosomesPhosphatidylinositol PhosphatesAnimalsCell MembraneEndocytosisHumansPhosphatidylinositol 3-KinasesPhosphatidylinositolsSignal Transductionphosphatidylinositol 3,4,5-triphosphatephosphatidylinositol 3,4-diphosphatePhosphatidylinositol 3-KinasesPhosphatidylinositol PhosphatesPhosphatidylinositols3-phosphoinositidecellular signalingfluorescent biosensorlysosomespatiotemporal regulation

Identifiers

PMID40127277
PMCPMC12002240

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.