ArticleBMC oral health2025
Oral frailty and its influencing factors in patients with cancer undergoing chemotherapy: a cross-sectional study.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence and influencing factors of oral frailty in cancer patients: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Systematic review and meta-analysis of oral frailty prevalence among older hospitalized patients.Frontiers in public health · 2025Pooled it
- Influencing factors of oral frailty in elderly patients with head and neck cancer: a multicenter, cross-sectional study.BMC oral health · 2026Observational
- Article
- Tablet Acceptability in Older Outpatients Undergoing Cancer Chemotherapy.Geriatrics (Basel, Switzerland) · 2026Article
- Development and validation of a nomogram prediction model for oral frailty in community-dwelling older adults.Frontiers in public health · 2026Article
- Machine learning for oral frailty factors in hospitalized schizophrenia patients: two-stage feature selection and SHAP analysis.Frontiers in psychiatry · 2026Article
- Mediating Role of Dyadic Coping Between Social Support and Oral Frailty Cross-Sectional Study of Elderly Ovarian Cancer Patients in China.International journal of women's health · 2026Article
- Cross-sectional study on oral frailty in elderly patients with periodontitis in Anhui.BMC oral health · 2025Article
- Prevalence and risk factors of oral frailty in elderly cancer inpatients: A cross-sectional study.Medicine · 2025Article
- Exploratory analysis of associations among weight loss, oral function, and dysgeusia in patients with lung cancer undergoing chemotherapy.BMC oral health · 2025Article
- Prevalence and influencing factors of oral frailty among middle-aged and older patients with chronic kidney disease: a cross-sectional study.Frontiers in medicine · 2025Article
- Network modeling of the impact of social support and illness acceptance on disease activity in Crohn's disease patients: a cross-sectional study.Frontiers in psychology · 2025Article
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11 authors.
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Abstract
backgroundOral frailty is one of the easily overlooked complications in patients with cancer, which is as important as dietary dysfunction, malnutrition and other complications. However, limited research exists on the factors influencing oral frailty in patients with cancer undergoing chemotherapy. The objective of this study is to investigate the incidence of oral frailty in patients with cancer undergoing chemotherapy and to analyze the factors that influence it.
methodsA convenience sampling method was used to select patients with cancer undergoing chemotherapy from three tertiary hospitals in Chengdu, Sichuan Province. The Oral Frailty Index-8 (OFI-8) was utilized to assess the patients' oral frailty status. The Chemotherapy-induced Taste Alteration Scale(CiTAS), the Acceptance of Illness Scale(AIS), and the Family Adaptation, Partnership, Growth, Affection, Resolve Index(APGAR) were used to assess the patients' taste changes, levels of acceptance of illness, and family functioning levels, respectively. Additionally, descriptive analysis, univariate analysis, and multiple linear stepwise regression analysis were conducted.
resultsThe incidence of oral frailty among patients with cancer undergoing chemotherapy was found to be 57.58%. Additionally, oral frailty was positively correlated with chemotherapy-induced taste alteration, while it was negatively correlated with acceptance of illness and family functioning. Furthermore, multiple linear stepwise regression analysis revealed that factors such as disease duration, history of radiation therapy, dry mouth, dentures, chemotherapy-induced taste alteration, acceptance of illness, and family functioning significantly influenced oral frailty in these patients, accounting for a total variance of 54.6%.
conclusionThe incidence of oral frailty is notably high among patients with cancer undergoing chemotherapy. Several factors, such as disease duration, history of radiation therapy, dry mouth, the use of dentures, chemotherapy-induced taste alteration, acceptance of illness, and family functioning, significantly affect the degree of oral frailty. This highlights the necessity for healthcare providers to implement preventive management strategies based on these factors, and to modify oral care plans accordingly to prevent or mitigate the onset and progression of oral frailty in patients with cancer undergoing chemotherapy.
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