Observational studyCardiovascular diabetology2025
Association between triglyceride-glucose index and mortality in critically ill patients with atrial fibrillation: a retrospective cohort study.
Observational study in Cardiovascular diabetology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Diabetes-TyG interaction and mortality in critical cerebrovascular disease: a retrospective cohort study.Scientific reports · 2026Article
- Reproducible bicarbonate thresholds predict critically ill patient mortality in an international personalized survival study.iScience · 2026Article
- Combined assessment of triglyceride-glucose index and stress hyperglycemia ratio to predict all-cause mortality in critically ill patients with intracerebral hemorrhage.BMC neurology · 2026Article
- Association Between Hemoglobin Glycation Index and Mortality in Critically Ill Patients With Atrial Fibrillation: A Retrospective Cohort Study.Clinical cardiology · 2026Article
- Burden and age-specific trends of atrial fibrillation/atrial flutter from 1990 to 2023: a growing challenge among younger and middle-aged adults.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- Dynamic association between triglyceride-glucose-body mass index and hospital mortality in critically ill patients with heart failure: a multicenter retrospective cohort study.Cardiovascular diabetology · 2026Observational
- Triglyceride-glucose index as a potential evaluation tool for all-cause mortality in ischemic stroke patients undergoing endovascular therapy: a multicenter cohort study.BMC endocrine disorders · 2026Observational
- The impact of magnesium sulfate administration on outcomes in ICU patients with acute myocardial infarction: a retrospective cohort study.Frontiers in pharmacology · 2026Article
- The C-reactive protein-triglyceride glucose index (CTI) predicts mortality in cardiovascular-kidney-metabolic syndrome: a dual-cohort study with machine learning validation.International journal of surgery (London, England) · 2026Article
- Prognostic value of the triglyceride-glucose index for ICU mortality in non-diabetic sepsis: a restricted cubic spline analysis.Frontiers in endocrinology · 2026Article
- Association between C-reactive protein to triglyceride-glucose index and atrial fibrillation: a cross-sectional analysis.Frontiers in endocrinology · 2026Article
- Elevated triglyceride-glucose index and acute kidney injury risk in critical atrial fibrillation: an analysis from MIMIC-IV.BMC cardiovascular disorders · 2025Article
- Inflammation and Albumin-Based Biomarkers Are Not Independently Associated with Mortality in Critically Ill COPD Patients: A Retrospective Study.Life (Basel, Switzerland) · 2025Article
- Association between trajectory of triglyceride-glucose index and all-cause mortality in critically ill patients with atrial fibrillation: a retrospective cohort study.Cardiovascular diabetology · 2025Observational
- Correction: Association between triglyceride-glucose index and mortality in critically ill patients with atrial fibrillation: a retrospective cohort study.Cardiovascular diabetology · 2025Article
- Distinct patterns of association between the hemoglobin glycation index, the stress-hyperglycemia ratio, and the risk of new-onset atrial fibrillation in critically ill patients.Frontiers in endocrinology · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
Abstract
backgroundThe triglyceride-glucose (TyG) index, an emerging surrogate marker of insulin resistance, has been implicated in adverse cardiovascular outcomes. However, its prognostic value in critically ill patients with atrial fibrillation (AF) remains unclear. This study aimed to investigate the association between the TyG index and all-cause mortality in this high-risk population.
methodsWe identified critically ill patients with AF from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database and categorized them into tertiles based on their TyG index levels. The primary outcome was 30-day mortality, with 90-day and 365-day all-cause mortality as secondary outcomes. Cox proportional hazards regression analysis and restricted cubic splines were used to elucidate the relationship between the TyG index and all-cause mortality. Kaplan-Meier survival analysis was performed to visualize survival differences among the tertiles.
resultsA total of 1473 patients were included; the 30-day, 90-day, and 365-day all-cause mortality rates were 26.8%, 33.3%, and 41.1%, respectively. Multivariate Cox proportional hazards analysis revealed that the TyG index was independently associated with mortality at 30 days [hazard ratio (HR) (95% confidence interval (CI)) 1.26 (1.09-1.45), P = 0.002], 90 days [HR (95% CI) 1.27 (1.11-1.45), P < 0.001], and 365 days [HR (95% CI) 1.24 (1.10-1.40), P < 0.001]. Restricted cubic splines regression showed a positive linear association between the TyG index and mortality risk. Kaplan-Meier survival curves further confirmed the significant survival disparities across TyG index tertiles.
conclusionsA significant linear association was observed between higher TyG index and increased all-cause mortality at 30, 90, and 365 days in critically ill patients with AF. This underscores the role of the TyG index as a key prognostic indicator for risk stratification and management in intensive care.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.