Evidence map›Paper›PMID 40129317›Full record

GuidelineUnited European gastroenterology journal2025

European Consensus on Malabsorption-UEG & SIGE, LGA, SPG, SRGH, CGS, ESPCG, EAGEN, ESPEN, and ESPGHAN. Part 1: Definitions, Clinical Phenotypes, and Diagnostic Testing for Malabsorption.

Marco Vincenzo Lenti, Heinz Florian Hammer, Ilja Tacheci, Rosa Burgos, Stephane Schneider, Anastasiou Foteini, Aleksejs Derovs, Jutta Keller, Ilse Broekaert, Marianna Arvanitakis and 20 more

Abstract readConsensus StatementPractice Guideline
In one paragraph

Guideline in United European gastroenterology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Autoimmune gastritis: emerging insights and clinical management.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Best of United European Gastroenterology Week 2025.United European gastroenterology journal · 2026
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Abdominal Bloating and Distension: Common Symptoms but Limited Evidence.United European gastroenterology journal · 2025
    Article
  12. Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Marco Vincenzo LentiDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.ORCID 0000-0002-6654-4911
Heinz Florian HammerDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University, Graz, Austria.ORCID 0000-0001-8683-4951
Ilja Tacheci2nd Department of Internal Medicine - Gastroenterology, Faculty of Medicine in Hradec Králové, University Hospital Hradec Králové, Charles University, Hradec Kralove, Czech Republic.
Rosa BurgosEndocrinology and Nutrition Department, Hospital Universitari Vall d'Hebron, Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain.
Stephane SchneiderGastroenterology and Nutrition, Centre Hospitalier Universitaire de Nice, Université Côte d'Azur, Nice, France.ORCID 0000-0001-6256-8169
Anastasiou Foteini4th Local Primary Care Team, Municipality Practice and Academic Practice of Heraklion, University of Crete, Heraklion, Greece.
Aleksejs DerovsDepartment of Internal Diseases, Rīga Stradiņš University, Riga, Latvia.ORCID 0000-0002-0252-0726
Jutta KellerIsraelitic Hospital, Academic Hospital University of Hamburg, Hamburg, Germany.ORCID 0000-0002-5884-1115
Ilse BroekaertDepartment of Paediatrics, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.ORCID 0000-0002-7802-3064
Marianna ArvanitakisDepartment of Gastroenterology, Digestive Oncology and Hepatopancreatology, HUB Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
Dan Lucian Dumitrascu2nd Department of Internal Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Oscar Segarra-CantónPaediatric Gastroenterology and Clinical Nutrition Unit, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
Željko KrznarićDepartment of Gastroenterology, Hepatology and Nutrition, University of Zagreb, Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Croatia.
Juris PokrotnieksDepartment of Internal Diseases, Rīga Stradiņš University, Riga, Latvia.ORCID 0000-0002-3937-1090
Gonçalo NunesGastroenterology Department, Hospital Garcia de Orta, Almada, Portugal.
Johann HammerDepartment of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-2452-1201
Loris PironiDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.ORCID 0000-0002-1773-8330
Marc SonyiClinic for General Medicine, Gastroenterology, and Infectious Diseases, Augustinerinnen Hospital, Cologne, Germany.
Cristina Maria Sabo2nd Department of Internal Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Juan MendiveLa Mina Primary Health Care Academic Centre, Catalan Health Institute, University of Barcelona, Barcelona, Spain.ORCID 0000-0001-8095-7707
Adrien NicolauGastroenterology and Nutrition, Centre Hospitalier Universitaire de Nice, Université Côte d'Azur, Nice, France.
Jernej DolinsekPediatric Gastroenterology, Hepatology and Nutrition Unit, Pediatric Department, University Medical Center Maribor, Maribor, Slovenia.
Denisa KyselovaDepartment of Hepatogastroenterology, IKEM, Prague, Czech Republic.ORCID 0000-0001-6652-653X
Lucrezia LaterzaDepartment of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0001-5515-1197
Antonio GasbarriniDepartment of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Rome, Italy.
Teodora Surdea-Blaga2nd Department of Internal Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Jorge FonsecaGastroenterology Department, Hospital Garcia de Orta, Almada, Portugal.
Christos LionisLaboratory of Health and Society, School of Medicine, University of Crete, Heraklion, Greece.ORCID 0000-0002-9324-2839
Gino Roberto CorazzaDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Antonio Di SabatinoDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.

Funding

United European GastroenterologyUniversity of Pavia
6 · The paper itself

Abstract

Malabsorption is a complex and multifaceted condition characterised by the defective passage of nutrients into the blood and lymphatic streams. Several congenital or acquired disorders may cause either selective or global malabsorption in both children and adults, such as cystic fibrosis, exocrine pancreatic insufficiency (EPI), coeliac disease (CD) and other enteropathies, lactase deficiency, small intestinal bacterial overgrowth (SIBO), autoimmune atrophic gastritis, Crohn's disease, and gastric or small bowel resections. Early recognition of malabsorption is key for tailoring a proper diagnostic work-up for identifying the cause of malabsorption. A patient's medical and pharmacological history is essential for identifying risk factors. Several examinations such as endoscopy with small intestinal biopsies, non-invasive functional tests and radiological imaging are useful in diagnosing malabsorption. Because of its high prevalence, CD should always be looked for in cases of malabsorption with no other obvious explanations and in high-risk individuals. Nutritional support is key in the management of patients with malabsorption; different options are available, including oral supplements, enteral or parenteral nutrition. In patients with short bowel syndrome, teduglutide proved effective in reducing the need for parenteral nutrition, thus improving the quality of life of these patients. Primary care physicians play a central role in the early detection of malabsorption and should be involved in multidisciplinary teams for improving the overall management of these patients. In this European consensus, involving ten scientific societies and several experts, we have dissected all the issues around malabsorption, including the definitions and diagnostic testing (Part 1), high-risk categories and special populations, nutritional assessment and management, and primary care perspective (Part 2).

Indexed as

GastroenterologyMalabsorption SyndromesConsensusEuropeExocrine Pancreatic InsufficiencyHumansIntestine, SmallPhenotypeSocieties, Medicalbreath testcoeliac diseasediarrhoeaenteropathynutritionpancreatitisweight loss

Identifiers

PMID40129317
PMCPMC12090837

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.