ArticleRadiology case reports2025
Periportal extramedullary hematopoiesis in a patient with primary myelofibrosis: A great mimicker of an infiltrating tumor in the liver.
Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of 47 published cases of extramedullary hematopoiesis in myelofibrosis: clinical patterns, treatment responses, and prognostic implications.Annals of hematology · 2026Pooled it
- Periportal Extramedullary Hematopoiesis With Bile Duct Dilatation: A Case Report of a Rare Condition.Cureus · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary myelofibrosis (PMF) is a rare and progressive bone marrow cancer characterized by fibrosis, abnormal megakaryocyte proliferation, and impaired blood cell production. We present a case of a 65-year-old male diagnosed with accelerated PMF and periportal extramedullary hematopoiesis. Despite a history of stable myelofibrosis, the patient developed progressive hepatosplenomegaly and persistent anemia. Imaging studies, including MRI and CT scans, revealed periportal masses concerning for malignant infiltrative process. Subsequent biopsies confirmed the diagnosis of a sclerosing extramedullary hematopoietic tumor. Treatment included JAK2 inhibitor therapy, blood transfusions, and an eventual bone marrow transplant. This case highlights the complexities in diagnosing and managing PMF, particularly with rare complications like periportal extramedullary hematopoiesis, and underscores the importance of integrating radiological and pathological findings for optimal management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.