Evidence map›Paper›PMID 40129967›Full record

ArticleBiochemistry and biophysics reports2025

Epigenome editing-mediated restoration of

Rio Miyadai, Shiori Hinata, Yuya Amemiya, Satori Shigematsu, Kazuhiro Umeyama, Hiroshi Nagashima, Kenji Yamatoya, Jun Ohgane

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Advances and clinical potential of epigenome editing.Cellular and molecular life sciences : CMLS · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rio MiyadaiLaboratory of Genomic Function Engineering, Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, 214-8571, Kanagawa, Japan.
Shiori HinataLaboratory of Genomic Function Engineering, Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, 214-8571, Kanagawa, Japan.
Yuya AmemiyaLaboratory of Genomic Function Engineering, Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, 214-8571, Kanagawa, Japan.
Satori ShigematsuLaboratory of Genomic Function Engineering, Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, 214-8571, Kanagawa, Japan.
Kazuhiro UmeyamaMeiji University International Institute for Bio-Resource Research (MUIIBR), Kawasaki, 214-8571, Kanagawa, Japan.
Hiroshi NagashimaMeiji University International Institute for Bio-Resource Research (MUIIBR), Kawasaki, 214-8571, Kanagawa, Japan.
Kenji YamatoyaLaboratory of Genomic Function Engineering, Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, 214-8571, Kanagawa, Japan.
Jun OhganeLaboratory of Genomic Function Engineering, Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, 214-8571, Kanagawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibrillin-1, an extracellular matrix protein encoded by the

Indexed as

CpG island shoredCas9-TET1DNA methylationEpigenome editingFBN1Haploinsufficiency

Identifiers

PMID40129967
PMCPMC11932662

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.