Evidence map›Paper›PMID 40130473›Full record

ReviewJournal of neurochemistry2025

Breaking the Mould: How the First Structure of a Deer Prion Suggests the Framework for Interspecies Strain Diversity and Transmission Barriers.

Szymon W Manka

Abstract readReview
In one paragraph

Review in Journal of neurochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Tracking Prions by RT-QuIC: An Update.Sub-cellular biochemistry · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Szymon W MankaDepartment of Infectious Disease, Imperial College London, London, UK.ORCID 0000-0001-6733-146X

Funding

Medical Research Council MR/X007332/1
6 · The paper itself

Abstract

Our Insight into the Structural Diversity of Prions Has Been Limited by Studies Focused on Rodent-Adapted Sheep (Scrapie) Prion Strains, Until Now. In a Recent Paper (Alam et al. 2024), the Caughey Research Group Presents the First Prion Structure from a Naturally Occurring Chronic Wasting Disease (CWD), Offering a Fresh Perspective.

Indexed as

PrionsWasting Disease, ChronicAnimalsDeerHumansSheepSpecies SpecificityPrions

Identifiers

PMID40130473
PMCPMC11934078

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.