Evidence map›Paper›PMID 40132449›Full record

ArticleNutrition (Burbank, Los Angeles County, Calif.)2025

Impact of a multicomponent food-as-medicine intervention on behavioral and mental health outcomes for patients with and without food insecurity.

Marcela D Radtke, June M Tester, Lan Xiao, Wei-Ting Chen, Benjamin O Emmert-Aronson, Elizabeth A Markle, Steven Chen, Lisa G Rosas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrition (Burbank, Los Angeles County, Calif.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marcela D RadtkePropel Postdoctoral Research Fellow, Stanford University School of Medicine, Stanford, California, USA; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, California, USA.
June M TesterOsher Center for Integrative Medicine and Department of Family and Community Medicine, University of California, San Francisco School of Medicine, San Francisco, California, USA; Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA.
Lan XiaoDepartment of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, California, USA.
Wei-Ting ChenDepartment of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, California, USA; Office of Community Engagement, Stanford University School of Medicine, Stanford, California, USA.
Benjamin O Emmert-AronsonOpen Source Wellness, Oakland, California, USA.
Elizabeth A MarkleOpen Source Wellness, Oakland, California, USA.
Steven ChenAlameda County Health, San Leandro, California, USA.
Lisa G RosasDepartment of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, California, USA; Office of Community Engagement, Stanford University School of Medicine, Stanford, California, USA; Department of Medicine, Division of Primary Care and Population Health, Stanford University School of Medicine, Stanford, California, USA. Electronic address: lgrosas@stanford.edu.

Funding

Effectiveness of Recipe4Health on Obesity and Cardiometabolic Health: A natural experimentR01DK140186 · NIDDK · STANFORD UNIVERSITY · PI Lisa Goldman Rosas, June M Tester · 2024 to 2026
$2.2M
NIDDK NIH HHS R01 DK140186
6 · The paper itself

Abstract

backgroundIncreasingly, food-as-medicine (FAM) programs are being implemented as a strategy for improving the health of patients. However, current policies limit nutrition resources to patients with specific chronic condition diagnoses and do not include food insecurity as a qualifying condition.

objectiveExplore the impact of Recipe4Health (R4H), a multicomponent FAM intervention, on behavioral and mental health outcomes in patients with and without food insecurity.

methodsPatients (n = 336) with diet-related chronic conditions and/or food insecurity were referred to R4H, which included 16-weekly produce deliveries and behavioral intervention sessions. Food security status was assessed using the U.S. Department of Agriculture 6-item survey. Outcomes included vegetable/fruit intake, physical activity (PA) and mental health. Within- and between-group pre-post changes were assessed using repeated-measures linear mixed-effects models, adjusting for baseline.

resultsThe majority of patients had one or more chronic conditions (96%) and identified as food insecure (62%). Patients with food insecurity experienced significant increases in daily servings of vegetables/fruit (+0.38 ± 0.15; P = 0.01) and minutes of moderate-to-vigorous PA per week (+28.94 ± 9.84; P < 0.01). Patients with food security did not experience significant increases in vegetables/fruit (P = 0.09) or PA (P = 0.06). Food-insecure and food-secure patients both experienced significant improvements in loneliness, anxiety, and depressive symptoms from baseline (P < 0.01 for all). Between-group differences were observed only for anxiety, where patients with food security experienced significant improvements in anxious symptoms compared to food-insecure patients (-1.24 [-2.33, -0.14]; P = 0.03).

conclusionPolicymakers may consider expanding eligibility criteria to include food insecurity as an independent qualifying condition for FAM.

Indexed as

DietFood InsecurityFood SupplyHealth PromotionMental HealthAdultAgedChronic DiseaseExerciseFemaleFruitHumansMaleMiddle AgedVegetablesBehavior changeChronic disease preventionFood as MedicineFood insecurityLifestyle modificationNutritionNutrition insecurityPhysical activityProduce prescription

Identifiers

PMID40132449
PMCPMC13592433

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.