ArticleNature2025
MFSD6 is an entry receptor for enterovirus D68.
Abstract read
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Carboxypeptidase A6 contributes to bovine enterovirus F production through apoptosis-associated PI3K/AKT/FOXO1 signaling.Virulence · 2026Article
- Cross-Neutralizing and Broadly Neutralizing Human Antibodies Against Nonenveloped Viruses.European journal of immunology · 2026Review
- A dual-receptor checkpoint primes enterovirus D68 for respiratory cell entry.Nature communications · 2026Article
- An RNA-to-RNA pipeline for rapid antiviral antibody development.Molecular therapy : the journal of the American Society of Gene Therapy · 2026Article
- Progress in enterovirus D68-neutralizing antibodies and vaccines.Journal of virology · 2026Review
- Open questions in enterovirus uncoating.Journal of virology · 2026Review
- Comparative immunogenic and structural analysis of virus-like particle and inactivated whole-virion vaccines against enterovirus D68.Molecular therapy. Nucleic acids · 2026Article
- Article
- EV-D68 exploits clathrin-mediated endocytosis and compensatory macropinocytosis for cellular entry.Journal of virology · 2026Article
- Decoding the complex receptor landscape of enterovirus D68.PLoS pathogens · 2026Review
- From CRISPR functional genomics to synthetic interventions: engineering antiviral strategies.Journal of virology · 2026Review
- Challenges in developing broad-spectrum viral attachment inhibitors targeting heparan sulfates and sialic acids.Journal of virology · 2026Review
- Advances in Antiviral Drug Development Targeting Enteroviruses: From Viral Proteins to Host Factors.Viruses · 2026Review
- Enterovirus D68 receptor usage: from static attachment to dynamic entry.Journal of virology · 2026Review
- Genome-wide CRISPR screening identifies Annexin A1 as a facilitator of porcine astrovirus entry.PLoS pathogens · 2026Article
- Review
- Neutralizing human monoclonal antibodies to poliovirus map to the receptor binding site.Nature communications · 2026Article
- Respiratory enterovirus D68: virology, clinical surveillance, host-pathogen interactions, and therapeutic prospects.Frontiers in cellular and infection microbiology · 2026Review
- Structural insights into cationic amino acid transport and viral receptor engagement by CAT1.Nature communications · 2025Article
- mRNA vaccine expressing enterovirus D68 virus-like particles induces potent neutralizing antibodies and protects against infection.Molecular therapy. Nucleic acids · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors.
Lauren Varanese *Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0003-3916-8401
Lily Xu *Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0002-1200-8937
Christine E PetersDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
Grigore PintilieDepartment of Bioengineering, Stanford University, Stanford, CA, USA.
David S RobertsSarafan ChEM-H, Stanford University, Stanford, CA, USA.ORCID 0000-0002-0478-4987
Suyash RajInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0002-0686-8201
Mengying LiuVirology Group, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Yaw Shin OoiProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.ORCID 0000-0001-9014-1365
Jonathan DiepDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0003-3876-2126
Wenjie QiaoDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0002-0255-6155
Christopher M RichardsDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
Jeremy CallawayInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Carolyn R BertozziSarafan ChEM-H, Stanford University, Stanford, CA, USA.ORCID 0000-0003-4482-2754
Sabrina JabsInstitute of Clinical Molecular Biology, Christian-Albrechts-University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.ORCID 0000-0001-8065-8002
Erik de VriesVirology Group, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Frank J M van KuppeveldVirology Group, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0001-5800-749X
Claude M NagamineDepartment of Comparative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Wah ChiuDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA. wahc@stanford.edu.ORCID 0000-0002-8910-3078
Jan E CaretteDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA. carette@stanford.edu.ORCID 0000-0002-5187-8070
Funding
The Stanford-SLAC CryoEM Center supplementU24GM129541 · NIGMS · STANFORD UNIVERSITY · PI CHIU, WAH, HEDMAN, BRITT · 2018 to 2023
$54.8MMOLECULAR BASIS OF HOST-PARASITE INTERACTIONT32AI007328 · NIAID · STANFORD UNIVERSITY · PI JUSTIN L SONNENBURG · 1987 to 2026
$11.9MInvestigating the Surface GlycoproteomeR01CA200423 · NCI · STANFORD UNIVERSITY · PI Carolyn Bertozzi · 2015 to 2026
$3.8MHuman 3D neuro-muscular assembloids to study cell tropism and host factor utilization of divergent neuropathogenic enterovirusesR01AI169467 · NIAID · STANFORD UNIVERSITY · PI Jan E Carette, Sergiu Pasca · 2022 to 2026
$3.7MHost determinants of enterovirus RNA replication and in vivo neuropathogenesisR01AI153169 · NIAID · STANFORD UNIVERSITY · PI CARETTE, JAN E · 2021 to 2025
$2.7MGenetic screens to find critical host factors for SARS-CoV-2 infectionR01AI140186 · NIAID · STANFORD UNIVERSITY · PI CARETTE, JAN E · 2019 to 2023
$2.3MCLINICAL/IMMUNOLOGIC/GENETIC ANALYSES OF AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROMEZ01AI000732 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI RAO, VEMULKONDA · 1995 to 2008
$1.1MFour Laser, 18 Color Cell Sorter in the SSFFS10RR025518 · NCRR · STANFORD UNIVERSITY · PI HERZENBERG, LEONARD A · 2009 to 2009
$500kIntramural NIH HHS Z01 AI000732NCI NIH HHS R01 CA200423NCRR NIH HHS S10 RR025518NIAID NIH HHS R01 AI140186NIAID NIH HHS R01 AI153169NIAID NIH HHS R01 AI169467NIAID NIH HHS T32 AI007328NIGMS NIH HHS U24 GM129541Wellcome Fund Investigators in the Pathogenesis of Infectious Disease
Abstract
With the near eradication of poliovirus due to global vaccination campaigns, attention has shifted to other enteroviruses that can cause polio-like paralysis syndrome (now termed acute flaccid myelitis)
Indexed as
Enterovirus D, HumanReceptors, VirusVirus InternalizationAnimalsCell LineCell MembraneCentral Nervous System Viral DiseasesCryoelectron MicroscopyEnterovirus InfectionsFemaleHumansMaleMiceModels, MolecularMyelitisNeuromuscular DiseasesReceptors, Virus
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.