Evidence mapPaperPMID 40133366Full record

ArticleScientific reports2025

Preoperative ECOG performance status as a predictor of outcomes in upper tract urothelial cancer surgery.

Tsung-Mu Yang, I-Hsuan Alan Chen, Chia-Cheng Yu, Chi-Rei Yang, Wen-Chi Chen, Po-Hung Lin, See-Tong Pang, Steven Kuan-Hua Huang, Zhi-Hao Chen, Jen-Shu Tseng and 15 more

Abstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Tsung-Mu YangDepartment of Urology, Kaohsiung Medical University Hospital, No. 100, Tzyou 1st Rd., Sanmin District, Kaohsiung, 807377, Taiwan.
I-Hsuan Alan ChenDivision of Urology, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Chia-Cheng YuDivision of Urology, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Chi-Rei YangDepartment of Urology, China Medical University Hospital, Taichung, Taiwan.
Wen-Chi ChenDepartment of Urology, China Medical University Hospital, Taichung, Taiwan.
Po-Hung LinDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
See-Tong PangDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Steven Kuan-Hua HuangDivision of Urology, Department of Surgery, Chi Mei Medical Center, Tainan, Taiwan.
Zhi-Hao ChenDivision of Urology, Department of Surgery, Chi Mei Medical Center, Tainan, Taiwan.
Jen-Shu TsengDepartment of Urology, MacKay Memorial Hospital, Taipei, Taiwan.
Wun-Rong LinDepartment of Urology, MacKay Memorial Hospital, Taipei, Taiwan.
Yao-Chou TsaiDepartment of Surgery, Taipei Tzu Chi Hospital, The Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.
Chih-Chin YuSchool of Medicine, Buddhist Tzu Chi University, Hualien, Taiwan.
Pi-Che ChenDepartment of Urology, Ditmanson Medical Foundation, Chiayi Christian Hospital, Chiayi, Taiwan.
Ian-Seng CheongDepartment of Urology, Ditmanson Medical Foundation, Chiayi Christian Hospital, Chiayi, Taiwan.
Yuan-Hong JiangDepartment of Urology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation and Tzu Chi University, Hualien, Taiwan.
Chia-Chang WuDepartment of Urology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Hsu-Che HuangDivision of Urology, Department of Surgery, Cardinal Tien Hospital, New Taipei City, Taiwan.
Ting-En TaiDepartment of Urology, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan.
Chung-You TsaiDivisions of Urology, Department of Surgery, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
Wei-Yu LinSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Yung-Tai ChenDepartment of Urology, Postal Hospital, Taipei, Taiwan.
Richard Chen-Yu WuDepartment of Urology, E-Da Hospital, Kaohsiung, Taiwan.
Hsiang-Ying LeeDepartment of Urology, Kaohsiung Medical University Hospital, No. 100, Tzyou 1st Rd., Sanmin District, Kaohsiung, 807377, Taiwan. ashum1009@hotmail.com.
Hsin-Chih YehDepartment of Urology, Kaohsiung Medical University Hospital, No. 100, Tzyou 1st Rd., Sanmin District, Kaohsiung, 807377, Taiwan. patrick1201.tw@yahoo.com.tw.

Funding

Kaohsiung Municipal Ta-Tung Hospital kmtth-111-R011Ministry of Science and Technology, Taiwan MOST 111-2314-B-037-071-MY3
6 · The paper itself

Abstract

Eastern Cooperative Oncology Group performance status (ECOG-PS) is a widely used functional status measure in oncology, yet its prognostic value in upper tract urothelial carcinoma remains unclear. In this multicenter study of 2473 patients undergoing radical nephroureterectomy, ECOG-PS ≥ 2 was independently associated with worse overall survival (hazard ratio [HR] 2.53, p < 0.001), cancer-specific survival (HR 2.02, p < 0.001), and disease-free survival (HR 1.50, p = 0.003) than those with ECOG-PS 0-1. They also had a higher risk of major perioperative complications (odds ratio 2.46, p < 0.001). These findings support ECOG-PS as a valuable preoperative risk stratification tool.

Indexed as

Carcinoma, Transitional CellUrologic NeoplasmsAgedAged, 80 and overFemaleHumansMaleMiddle AgedNephroureterectomyPreoperative PeriodPrognosisTreatment OutcomeEastern cooperative oncology groupMajor perioperative complicationRadical nephroureterectomySurvival outcomeUpper tract urothelial carcinoma

Identifiers

PMID40133366
PMCPMC11937394

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.