Evidence map›Paper›PMID 40133503›Full record

ReviewNature reviews. Microbiology2025

Ecology, global diversity and evolutionary mechanisms in the Mycobacterium tuberculosis complex.

Galo A Goig, Etthel M Windels, Chloé Loiseau, Christoph Stritt, Loza Biru, Sonia Borrell, Daniela Brites, Sebastien Gagneux

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Article
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  4. Mce transport systems inJournal of bacteriology · 2026
    Review
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  6. Antimicrobial agents and chemotherapy · 2026
    Article
  7. Article
  8. Article
  9. Review
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  11. Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Galo A GoigMedical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.ORCID http://orcid.org/0000-0002-4136-6610
Etthel M WindelsMedical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.ORCID http://orcid.org/0000-0003-2106-6765
Chloé LoiseauMedical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
Christoph StrittMedical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.ORCID http://orcid.org/0000-0002-3167-6658
Loza BiruMedical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
Sonia BorrellMedical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
Daniela BritesMedical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
Sebastien GagneuxMedical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland. sebastien.gagneux@swisstph.ch.ORCID http://orcid.org/0000-0001-7783-9048

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the COVID-19 pandemic receding, tuberculosis (TB) is again the number one cause of human death to a single infectious agent. TB is caused by bacteria that belong to the Mycobacterium tuberculosis complex (MTBC). Recent advances in genome sequencing have provided new insights into the ecology and evolution of the MTBC. This includes the discovery of new phylogenetic lineages within the MTBC, a deeper understanding of the host tropism among the various animal-adapted lineages, enhanced knowledge on the evolutionary dynamics of antimicrobial resistance and transmission, as well as a better grasp of the within-host MTBC diversity. Moreover, advances in long-read sequencing are increasingly highlighting the relevance of structural genomic variation in the MTBC. These findings not only shed new light on the biology and epidemiology of TB, but also give rise to new questions and research avenues. The purpose of this Review is to summarize these new insights and discuss their implications for global TB control.

Indexed as

Mycobacterium tuberculosisTuberculosisAnimalsCOVID-19Evolution, MolecularGenetic VariationGenome, BacterialHumansPhylogenySARS-CoV-2

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.