Evidence map›Paper›PMID 40133504›Full record

ArticleScientific reports2025

Investigating the chemical composition and antifungal effect of Cinnamomum cassia essential oil against Saccharomyces cerevisiae and Acremonium sp.

Fairouz Boubrik, Tahar Boubellouta, Nabil Benyoucef, Yuva Bellik, Lynda Gali, Abdullah Akdoğan, Dmitry E Kucher, Aleksandra O Utkina, Olga D Kucher, Nazih Y Rebouh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Anticandidal activity ofFrontiers in pharmacology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fairouz BoubrikLaboratory of Characterization and Valorization of Natural Resources (L.C.V.R), Faculty of Life and Natural Sciences and of Earth and Universe Sciences, Mohamed El Bachir El Ibrahimi University, Bordj Bou Arreridj, 34000, Algeria.
Tahar BoubelloutaLaboratory of Characterization and Valorization of Natural Resources (L.C.V.R), Faculty of Life and Natural Sciences and of Earth and Universe Sciences, Mohamed El Bachir El Ibrahimi University, Bordj Bou Arreridj, 34000, Algeria.
Nabil BenyoucefBIOGEP Laboratory-Ecole Nationale Polytechnique ENP-El-Harrach, Alger, 16200, Algeria.
Yuva BellikLaboratory of Characterization and Valorization of Natural Resources (L.C.V.R), Faculty of Life and Natural Sciences and of Earth and Universe Sciences, Mohamed El Bachir El Ibrahimi University, Bordj Bou Arreridj, 34000, Algeria.
Lynda GaliBiotechnology Research Center-CRBt, Constantine, Algeria.
Abdullah AkdoğanChemical Engineering Department, Faculty of Engineering, Pamukkale University, Denizli, 20017, Turkey.
Dmitry E KucherDepartment of Environmental Management, Institute of Environmental Engineering, RUDN University, 6 Miklukho-Maklaya St., Moscow, 117198, Russia.
Aleksandra O UtkinaDepartment of Environmental Management, Institute of Environmental Engineering, RUDN University, 6 Miklukho-Maklaya St., Moscow, 117198, Russia.
Olga D KucherDepartment of Environmental Management, Institute of Environmental Engineering, RUDN University, 6 Miklukho-Maklaya St., Moscow, 117198, Russia.
Nazih Y RebouhDepartment of Environmental Management, Institute of Environmental Engineering, RUDN University, 6 Miklukho-Maklaya St., Moscow, 117198, Russia. n.yacer16@outlook.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Essential oils are promising, safe, and eco-friendly alternatives to chemical fungicides. This study aimed to develop an effective biological control agent using Cinnamomum cassia essential oil (CCEO) as potential fungicidal agent against Saccharomyces cerevisiae and Acremonium sp, both isolated from natural orange juice. The yield, chemical composition and antifungal activity of CCEO were evaluated. The essential oil was extracted via hydro-distillation, and its composition was analyzed using gas chromatography-mass spectrometry (GC-MS). The antifungal activity was assessed using the disk diffusion agar method. Minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) were determined using microdilution methods. The extraction yield was 2.8%. (E)-cinnamaldehyde was identified as the major compound (37.72%). Inhibition zones ranged from 51 mm to 80 mm against Saccharomyces cerevisiae and from 75 mm to 90 mm against Acremonium sp. Equal MIC and MFC values were recorded for both fungal strains: MIC = MFC = 6.25% against Saccharomyces cerevisiae and MIC = MFC = 3.125% against Acremonium sp. These findings demonstrate for the first time that CCEO could be a promising antifungal agent against the two primary fungal contaminants of fruit products, Saccharomyces cerevisiae and Acremonium sp.

Indexed as

AcremoniumAntifungal AgentsCinnamomum aromaticumOils, VolatileSaccharomyces cerevisiaeGas Chromatography-Mass SpectrometryMicrobial Sensitivity TestsAntifungal AgentsOils, VolatileAcremonium spAntifungal activityChemical compositionCinnamomum cassia essential oilOrange juiceSaccharomyces cerevisiae

Identifiers

PMID40133504
PMCPMC11937399

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.