Evidence map›Paper›PMID 40133640›Full record

ArticleEye (London, England)2025

Descemet membrane endothelial keratoplasty with or without overnight admission.

Giulia Coco, Luca Pagano, Alfredo Borgia, Mahmoud Ahmed, Davide Tucci, Kunal A Gadhvi, Stephen B Kaye, Vito Romano

Abstract read
In one paragraph

Article in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giulia CocoOphthalmology, Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Rome, Italy. giulia.coco@uniroma2.it.ORCID http://orcid.org/0000-0002-2410-6366
Luca PaganoDepartment of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.ORCID http://orcid.org/0000-0001-8534-6817
Alfredo BorgiaDepartment of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.ORCID http://orcid.org/0000-0002-3976-242X
Mahmoud AhmedDepartment of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Davide TucciDepartment of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.ORCID http://orcid.org/0000-0002-1907-7900
Kunal A GadhviDepartment of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Stephen B KayeDepartment of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Vito RomanoDepartment of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.ORCID http://orcid.org/0000-0002-5148-7643

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare visual outcomes and show postoperative complication rates of Descemet Membrane Endothelial Keratoplasty (DMEK) with or without overnight admission.

methodsRetrospective analysis of DMEK surgeries performed at the Royal Liverpool University Hospital from 2018 to 2023. Data on demographics, surgical details, intraoperative and postoperative complications and admission type were collected. Visual outcomes and complication rates of surgeries with or without overnight admission were evaluated.

results344 eyes were included with mean patients' age of 72.1 ± 9.7 years (range 37.4-96.6 years). After surgery, 61.3% of patients (n = 211) were hospital-admitted for a one-night stay while 38.7% (n = 133) were home-discharged on the same day. Intraoperative complications occurred in 8.7% of patients and postoperative complications in 5.8%, with no difference with or without overnight admission (p = 0.308 and p = 0.412, respectively). There was no difference in the improvement in visual acuity (0.43 ± 0.6 and 0.45 ± 0.6 logMAR; range: -1.82; +2.38 logMAR) between both groups (p = 0.984), and no difference was found in postoperative rebubbling rate between both groups (30.8% in hospital-admitted and 31.6% in home-discharged; p = 0.926). Multivariate logistic regression showed no association between overnight admission and DMEK rebubbling rate (p = 0.555). However, postoperative complications, triple procedure and recipient age were all significant factors increasing DMEK rebubbling requirement (p < 0.05). Home-discharged patients had a risk ratio of 1.03 (95% CI 0.74-1.41; p = 0.926) for rebubbling and 0.68 (95% CI 0.28-1.372; p = 0.412) for postoperative complications compared to their hospital-admitted counterpart.

conclusionsVisual outcomes and postoperative complications did not show any significant difference in DMEK surgeries with or without overnight admission.

Indexed as

Corneal DiseasesDescemet Stripping Endothelial KeratoplastyHospitalizationAdultAgedAged, 80 and overFemaleHumansIntraoperative ComplicationsMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesVisual Acuity

Identifiers

PMID40133640
PMCPMC12130300

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.