Evidence map›Paper›PMID 40133732›Full record

ArticleActa neurologica Belgica2025

Setting multidisciplinary intervention goals for spinal muscular atrophy patients utilizing the international classification of functioning, disability, and health: a pilot study in a small sample sizes.

Gabriele Giannotta, Marta Ruggiero, Greta Pirani, Maria Carmela Oliva, Camilla Ferrante, Antonio Trabacca

Abstract read
In one paragraph

Article in Acta neurologica Belgica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gabriele Giannotta *Associazione "La Nostra Famiglia"- IRCCS "E. Medea" - Scientific Hospital for Neurorehabilitation - Unit for Severe Disabilities in Developmental Age and Young Adults (Developmental Neurology and Neurorehabilitation), Brindisi, Italy.ORCID http://orcid.org/0000-0002-1129-1689
Marta Ruggiero *Associazione "La Nostra Famiglia"- IRCCS "E. Medea" - Scientific Hospital for Neurorehabilitation - Unit for Severe Disabilities in Developmental Age and Young Adults (Developmental Neurology and Neurorehabilitation), Brindisi, Italy.ORCID http://orcid.org/0000-0001-9038-640X
Greta PiraniAssociazione "La Nostra Famiglia"- IRCCS "E. Medea" - Scientific Hospital for Neurorehabilitation - Unit for Severe Disabilities in Developmental Age and Young Adults (Developmental Neurology and Neurorehabilitation), Brindisi, Italy.ORCID http://orcid.org/0000-0001-8646-8752
Maria Carmela OlivaAssociazione "La Nostra Famiglia"- IRCCS "E. Medea" - Scientific Hospital for Neurorehabilitation - Unit for Severe Disabilities in Developmental Age and Young Adults (Developmental Neurology and Neurorehabilitation), Brindisi, Italy.ORCID http://orcid.org/0000-0003-2854-5638
Camilla FerranteAssociazione "La Nostra Famiglia"- IRCCS "E. Medea" - Scientific Hospital for Neurorehabilitation - Unit for Severe Disabilities in Developmental Age and Young Adults (Developmental Neurology and Neurorehabilitation), Brindisi, Italy.ORCID http://orcid.org/0000-0002-1752-2177
Antonio TrabaccaScientific Institute I.R.C.C.S. "E. Medea", Scientific Direction, Bosisio Parini (LC), Via Don L. Monza 20, 23842, Bosisio Parini (LC), Italy. antonio.trabacca@lanostrafamiglia.it.ORCID http://orcid.org/0000-0003-3165-0105

Funding

Italian Ministry of Health Ricerca CorrentePNRR PNRR-MR1-2022-12376937
6 · The paper itself

Abstract

backgroundSpinal Muscular Atrophy (SMA) is a genetic neuromuscular disorder causing progressive motor function loss, respiratory and swallowing impairments, and significant limitations in activities of daily living (ADLs) and social participation. While gene therapies have enhanced life expectancy, functional management remains crucial. Despite the International Classification of Functioning Disability and Health for Children and Youth (ICF-CY) being a valuable framework for patient-centered care, its integration in setting multidisciplinary rehabilitation goals for SMA patients is underexplored.

objectiveThis study aimed to assess the use of the ICF-CY framework in developing multidisciplinary intervention goals for SMA patients.

methodsA cross-sectional study involving 6 SMA patients was conducted at a pediatric neurorehabilitation hospital. Data were collected using a standardized ICF-CY-based case record form and analysed to identify patterns of impairment, activity limitations, and environmental factors.

resultsResults demonstrated the multifaceted nature of SMA, with significant impairments in motor function, respiratory function, and swallowing, as well as limitations in activities of daily living and social participation. Environmental factors, particularly social support and accessibility, emerged as crucial determinants of overall well-being.

conclusionsThe study underscores the importance of a multidisciplinary approach and the use of ICF-CY framework for developing comprehensive and patient-centered care plans for SMA patients.

Indexed as

International Classification of Functioning, Disability and HealthMuscular Atrophy, SpinalActivities of Daily LivingAdolescentChildChild, PreschoolCross-Sectional StudiesDisability EvaluationFemaleHumansMalePilot ProjectsDisabilityDisability and healthInternational classification of functioningMultidisciplinarityPatient-Centered careSpinal muscular atrophy

Identifiers

PMID40133732
PMCPMC12518437

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.