Evidence map›Paper›PMID 40133896›Full record

ArticleBMC public health2025

Exploring reported causes of vaccine hesitancy among European adolescents and parents: results of a citizen science project.

Pere Millat-Martínez, Ana Mora, Pol Ezquerra Condeminas, Miquel Castelló, Claudia Alsina, Beatriz Fiestas, Matteo Bason, Montserrat Esquerda, Alexandre Perera-LLuna, Begonya Nafria and 1 more

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
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  8. Causes and consequences of undervaccination in adults.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pere Millat-MartínezISGlobal, Barcelona, Spain. pere.millat@isglobal.org.
Ana MoraClinical Study Unit - Sanofi, Barcelona, Spain.
Pol Ezquerra CondeminasBeyond You, Barcelona, Spain.
Miquel CastellóBeyond You, Barcelona, Spain.
Claudia AlsinaInstitut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.
Beatriz FiestasISGlobal, Barcelona, Spain.
Matteo BasonFondazione Penta ETS, Padova, Italy.
Montserrat EsquerdaInstitut Borja de Bioètica- Universitat Ramon Llull, Esplugues de Llobregat, Barcelona, Spain.
Alexandre Perera-LLunaDepartament d'Enginyeria de Sistemes, Automàtica i Informàtica Industrial, B2SLab, Universitat Politècnica de Catalunya, Barcelona, Spain.
Begonya Nafria *Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.
Quique Bassat *ISGlobal, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProgress in pediatric immunization is threatened by vaccine hesitancy. While recent estimates show 14-35% of European parents exhibit some degree of hesitancy, little is known about adolescents. We assessed vaccine hesitancy and associated factors in European adolescents and parents through the online Science4Pandemics platform.

methodsWe conducted two cross-sectional surveys. One in individuals aged ≥ 12 and < 18 years, using a non-validated questionnaire adapted from the Parent Attitudes about Childhood Vaccines (PACV); and another using the PACV questionnaire in parents aged ≥ 18 years, who were not necessarily related to the adolescents.

results1877 adolescents from Italy, Portugal, Poland and Spain were included. Of these, 45.9% were aged 12-14 years, and 54.1% were 15-17 years. The prevalence of hesitancy (adapted PACV score ≥ 50%) was 20.8% (390 individuals). Hesitancy prevalence varied between countries, from 12.5% in Spain to 31.6% in Poland (p < 0.001). Geographic region was the only associated factor for hesitancy [Odds Ratio (OR) for Polish adolescents: 3.20 (95%CI: 2.29, 4.51); OR for Italian adolescents: 2.28 (95%CI: 1.62, 3.24); OR for Portuguese adolescents: 1.13 (95%CI: 0.77, 1.66); all compared to Spanish adolescents]. Country remained the only associated factor in the multivariate logistic regression analysis. In contrast, 1135 parents of children under 18 were included, with hesitancy observed in 20.4% (232 individuals). The main associated factors for hesitancy, both in the univariate and multivariate analyses, were country of residence [OR for Italian parents: 2.34 (95%CI: 1.47, 3.80); OR for Polish parents: 2.69 (95%CI: 1.70, 4.36); OR for Portuguese parents: 2.26 (95%CI: 1.41, 3.68); all compared to Spanish parents], and age, with older parents being less hesitant (OR: 0.97, 95%CI: 0.96, 1.00). In both parents and adolescents, the main reasons for vaccine hesitancy were fear of vaccine side effects (56.1% in adolescents, 51.9% in parents) and lack of trust in government recommendations (21.9% in adolescents, 22.8% in parents).

conclusionsVaccine hesitancy in adolescents and parents in Europe is prevalent, with country of residence as a key influencing factor. Targeted strategies to educate both groups about immunization benefits and its side effects are essential, considering the heterogeneity across countries and reasons for hesitancy.

Indexed as

ParentsVaccination HesitancyAdolescentAdultChildCross-Sectional StudiesEuropeFemaleHumansMaleSurveys and QuestionnairesAdolescentsCitizen scienceImmunizationParentsVaccinationVaccine hesitancy

Identifiers

PMID40133896
PMCPMC11938604

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.