Evidence map›Paper›PMID 40134053›Full record

ReviewAsia Pacific journal of clinical nutrition2025

Diet and the gut microbiota profiles in individuals at risk of chronic heart failure - A review on the Asian population.

Farhan S Fadhillah, Kona'atul Habibah, Achmad Z Juniarto, Mochamad A Sobirin, Nani Maharani, Adriyan Pramono

Abstract readReview
In one paragraph

Review in Asia Pacific journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Farhan S Fadhillah *Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang, Indonesia.
Kona'atul Habibah *Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang, Indonesia.
Achmad Z JuniartoDepartment of Medical Study, Faculty of Medicine, Diponegoro University, Semarang, Indonesia.
Mochamad A SobirinDepartment of Medical Study, Faculty of Medicine, Diponegoro University, Semarang, Indonesia.
Nani MaharaniDepartment of Medical Study, Faculty of Medicine, Diponegoro University, Semarang, Indonesia.
Adriyan PramonoDepartment of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang, Indonesia. Email: adriyanpramono@fk.undip.ac.id; adri-yanpramono@lecturer.undip.ac.id.

Funding

Institute for Research and Community Services (LPPM), Diponegoro University 357-08/UN7.D2/PP/IV/2024
6 · The paper itself

Abstract

BACKGROUND AND

objectivesChronic Heart Failure (CHF) is one of the leading cardiovascular diseases (CVDs), particularly in the Asian population. Individuals with specific health risks, such as obesity, type 2 diabetes, hypertension, dyslipidemia, and coronary artery disease (CAD), are more susceptible to developing CHF. Current evidence is limited to understanding the link between gut microbiota dysbiosis and CHF. Therefore, this review aims to explore the potential connection between dietary patterns, gut microbiota, and its metabolites in individuals at risk of CHF in the Asian population. METHODS AND STUDY

designA literature review of cross-sectional studies was conducted using primary keywords such as "Asian", "obesity", "type 2 diabetes", "hypertension", "dyslipidemia", "coronary artery disease", and "chronic heart failure". There was no restriction on sample size.

resultsSeveral gut microbiotas were found to correlate with CHF risk factors. There were increased levels of Prevotella, Klebsiella, Romboutsia, Catenibacterium, Clostridium, Holdemanella, Ruminococcus, Coprococcus, Parabacteroides, Bacteroides, Lachnoclostridium, Streptococcus, and Megamonas, while decreased levels of Oscillibacter, Bifidobacterium, Lactobacillus, Akkermansia, Roseburia, Faecalibacterium, Pseudobutyrivibrio, and Eubacterium were reported. These microbiota shifts were linked to increased TMAO production and impaired short-chain fatty acids (SCFAs) production. Dietary intake and microbial metabolites were also identified as contributors to the gut microbiota associated with CHF.

conclusionsA potential link exists between the gut microbiota profile and CHF risk factors, possibly mediated by microbial metabolites. Dietary patterns may influence CHF-associated gut microbiota and me-tabolites. Future research is needed to investigate how dietary modifications can modulate gut microbiota and its metabolites in CHF patients.

Indexed as

DietGastrointestinal MicrobiomeHeart FailureAsian PeopleChronic DiseaseHumansRisk FactorsAsiancardiovascular diseaseschronic heart failuregut microbiotarisk factors

Identifiers

PMID40134053
PMCPMC11937497

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.