Evidence map›Paper›PMID 40134107›Full record

GuidelineThe Medical journal of Australia2025

2024 Royal Australian College of General Practitioners and Healthy Bones Australia guideline for osteoporosis management and fracture prevention in postmenopausal women and men over 50 years of age.

Peter Wong, Weiwen Chen, Dan Ewald, Christian Girgis, Morton Rawlin, John Tsingos, Justine Waters

Abstract readPractice Guideline
In one paragraph

Guideline in The Medical journal of Australia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Article
  5. Review
  6. From Risk to Treatment: Clinical Updates in Osteoporosis Management.International journal of rheumatic diseases · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The effectiveness of bisphosphonates vs denosumab in people with dementia or frailty post hip fracture: a multi-database cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Follow-on osteoporosis therapy after denosumab discontinuation among Medicare beneficiaries.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  17. Article
  18. Review
  19. Implementing pharmacist-led home medicines reviews within fracture liaison services for better post-fracture care: a qualitative study of patient and practitioner experience.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peter WongWestmead Hospital, Sydney, NSW.
Weiwen ChenGarvan Institute, Sydney, NSW.
Dan EwaldUniversity Centre for Rural Health, University of Sydney, Lismore, NSW.
Christian GirgisWestmead Hospital, Sydney, NSW.
Morton RawlinUniversity of Sydney, Sydney, NSW.
John TsingosSouths Juniors Medical Centre, Sydney, NSW.
Justine WatersUniversity of Technology Sydney, Sydney, NSW.

Funding

Australian Government Department of Health and Aged Care
6 · The paper itself

Abstract

introductionThis updated guideline replaces the previous Royal Australian College of General Practitioners and Osteoporosis Australia (now, Healthy Bones Australia) guideline from 2017. The accumulation of high quality evidence supporting improvements in clinical practice over the past five years, need for expert consensus and opinion, and new developments in pharmacological management of osteoporosis, especially the role of osteoanabolic therapies, prompted this update. The aim was to provide clear, evidence-based recommendations to assist Australian general practitioners in managing patients over 50 years of age with poor bone health. However, it is useful for any health care professional caring for people with poor bone health and for health administrators and bureaucrats responsible for resource provision and allocation. MAIN RECOMMENDATIONS: Earlier recognition of poor bone health using clinical risk factors, and use of an absolute fracture risk assessment tool, particularly FRAX (https://fraxplus.org/), is encouraged. Widespread population-based osteoporosis screening is not recommended in Australia due to lack of supporting evidence. It is important to recognise patients with "imminent" or "very high" fracture risk, as this is a group in whom to consider early osteoanabolic therapy. Calcium and vitamin D supplementation are more effective in reducing fracture risk when given to individuals who have calcium and vitamin D deficiency (not to healthy non-institutionalised individuals). CHANGES IN ASSESSMENT AND MANAGEMENT AS A RESULT OF THE GUIDELINE: This guideline provides recommendations for the use of fracture risk assessment tools, particularly FRAX, for risk stratification, addresses the risk of rebound vertebral fracture following denosumab cessation, discusses removal of strontium as a therapy, clarifies "imminent" or "very high" fracture risk in patients and highlights the importance of calcium and vitamin D status, and the early use of osteoanabolic therapies. The full guideline is freely available at https://www.racgp.org.au/clinical-resources/clinical-guidelines/key-racgp-guidelines/view-all-racgp-guidelines/osteoporosis/executive-summary.

Indexed as

OsteoporosisOsteoporosis, PostmenopausalOsteoporotic FracturesAgedAustraliaBone Density Conservation AgentsFemaleHumansMaleMiddle AgedRisk AssessmentRisk FactorsVitamin DBone Density Conservation AgentsVitamin DboneFracturesGeneral practiceGuidelines as topicOsteoporosis

Identifiers

PMID40134107
PMCPMC12088310

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.