ReviewRSC advances2025
Aqueous two-phase system (ATPS): from basic science to applications.
Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- A Microcapsule-Integrated smRandom-seq Platform Enables Fixation-Free Single Microbe RNA Sequencing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Solvent Interaction Analysis: A New Lens for Protein Structure and Diagnostics.International journal of molecular sciences · 2026Review
- Aqueous Two-Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells.Advanced healthcare materials · 2026Article
- Therapeutic Potential and Sustainable Bioprocessing of Enterocin CC2: A Probiotic-Derived Antimicrobial Targeting Streptococcus mutans in Oral Health.Probiotics and antimicrobial proteins · 2026Article
- Ultrasound-assisted aqueous two-phase extraction of flavonoids from erigeron breviscapus: process optimization, structural characterization, antioxidant study, and DFT calculation.Scientific reports · 2026Article
- Mild One-Step Protein Recovery from Microalgae Cultivated in Swine Wastewater Using Natural Deep Eutectic Solvent-Based Aqueous Biphasic Systems.Molecules (Basel, Switzerland) · 2026Article
- Plant-Derived Nanovesicles: Resolving Conceptual Confusion, Overcoming Isolation Challenges, and Advancing Translational Potential.International journal of nanomedicine · 2026Review
- The Role of Nonconventional Technologies in the Extraction Enhancement and Technofunctionality of Alternative Proteins from Sustainable Sources.Foods (Basel, Switzerland) · 2025Review
- Direct visualization of phase-separation multiphase flow in a silica bead-packed microchannel using fluorescence microscopy.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025Article
- Cell Partitioning Design for Microfluidic ATPS Devices: A Dynamic Energy Strategy and Calculation Using Chondrocytes and Model Microparticles.Micromachines · 2025Article
- Application of commercial ultrafiltration membranes for protein purification by high performance countercurrent membrane purification (HPCMP).Biotechnology progressArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aqueous two-phase system (ATPS) epitomize a remarkable phenomenon where two immiscible phases manifest through the amalgamation of at least two water-soluble components at precise concentrations. Revered as an economically sustainable and environmentally harmonious technique for liquid-liquid separation, this method boasts extensive utility in the isolation and refinement of biomolecules, owing to its innate simplicity, cost-effectiveness, and compatibility with biological systems. The principal aim of this article is to provide a comprehensive overview of the fundamental principles governing phase formation in ATPS. It endeavors to elucidate the influential factors dictating this phenomenon and expound upon the construction of phase diagrams, which serve as pivotal tools in comprehending and manipulating ATPS behavior. Furthermore, the article delves into the diverse domains that reap benefits from ATPS applications. These encompass, yet transcend, the extraction of metal ions, elimination of pharmaceutical residues, environmental restoration, strides in biomedical sciences, and the recovery of dyes. In this pursuit, it strives to illuminate the manifold strengths and limitations of ATPS, offering a holistic understanding of its potential and existing challenges.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.