Evidence map›Paper›PMID 40134804›Full record

ReviewFrontiers in endocrinology2025

Crosstalk of TGF-β and somatostatin signaling in adenocarcinoma and neuroendocrine tumors of the pancreas: a brief review.

Hendrik Ungefroren, Harpal Randeva, Hendrik Lehnert, Jörg Schrader, Jens-Uwe Marquardt, Björn Konukiewitz, Ralf Hass

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Recent Advances in the Mechanisms and Applications ofMolecules (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hendrik UngefrorenInstitute of Pathology, University Hospital Schleswig-Holstein (UKSH), Campus Kiel, Kiel, Germany.
Harpal RandevaUniversity Hospital of Coventry and Warwickshire (UHCW) and Warwick Medical School, Coventry, United Kingdom.
Hendrik LehnertUniversity Hospital of Coventry and Warwickshire (UHCW) and Warwick Medical School, Coventry, United Kingdom.
Jörg SchraderFirst Department of Medicine, Universitätsklinikum Hamburg-Eppendorf (UKE), Hamburg, Germany.
Jens-Uwe MarquardtFirst Department of Medicine, University Hospital Schleswig-Holstein (UKSH), Campus Lübeck, Lübeck, Germany.
Björn KonukiewitzInstitute of Pathology, University Hospital Schleswig-Holstein (UKSH), Campus Kiel, Kiel, Germany.
Ralf HassBiochemistry and Tumor Biology Laboratory, Department of Obstetrics and Gynecology, Hannover Medical School, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the vast majority of cancers affecting the human pancreas are pancreatic ductal adenocarcinomas (PDAC), there are several other cancer types originating from non-exocrine cells of this organ,

Indexed as

AdenocarcinomaNeuroendocrine TumorsPancreatic NeoplasmsSignal TransductionSomatostatinTransforming Growth Factor betaAnimalsEpithelial-Mesenchymal TransitionHumansSomatostatinTransforming Growth Factor betaneuroendocrine tumorspancreaspancreatic ductal adenocarcinomasignalingsomatostatinTGF-β

Identifiers

PMID40134804
PMCPMC11934628

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.