Evidence map›Paper›PMID 40135114›Full record

ArticlePatient preference and adherence2025

Clinical Practice Evidence of Treatment Satisfaction with Moderate and High-Efficacy Drugs in Multiple Sclerosis.

Francisco Javier Barrero Hernández, Ángel José Morales Lahoz, Cristina Serrano Gutiérrez, Elena López Fandila, Carolina Asenjo Martín, Maria Dolores González Ramírez, Raquel Piñar-Morales

Abstract read
In one paragraph

Article in Patient preference and adherence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Francisco Javier Barrero HernándezDepartment of Neurology, Hospital Clinico Universitario San Cecilio, Granada, Spain.ORCID 0009-0007-1843-9002
Ángel José Morales LahozDepartment of Neurology, Hospital Clinico Universitario San Cecilio, Granada, Spain.
Cristina Serrano GutiérrezDepartment of Neurology, Hospital Clinico Universitario San Cecilio, Granada, Spain.
Elena López FandilaDepartment of Neurology, Hospital Clinico Universitario San Cecilio, Granada, Spain.
Carolina Asenjo MartínDepartment of Neurology, Hospital Clinico Universitario San Cecilio, Granada, Spain.
Maria Dolores González RamírezDepartment of Medicine, Faculty of Medicine. University of Granada, Granada, Spain.
Raquel Piñar-MoralesDepartment of Neurology, Hospital Clinico Universitario San Cecilio, Granada, Spain.ORCID 0000-0003-3490-4932

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Generally, the choice of disease-modifying treatment (DMT) for people with multiple sclerosis (PwMS) is based on aspects of efficacy and safety. However, due to the diversity of drugs and the different routes of administration, it is essential to know the experience and satisfaction of PwMS. Patient- reported outcomes (PROs) help us to optimize and improve adherence. Methods: Our objective with this cross-sectional, non-interventional study is to analyze satisfaction outcomes using the treatment satisfaction questionnaire for medication (TSQM) according to moderate or high efficacy of DMTs and the relationship with demographic, clinical and quality of life (QoL) aspects. Results: PwMS receiving high-efficacy DMTs show greater overall satisfaction, but not in the other TSQM subscales. The route of administration did not show differences in treatment satisfaction. The best QoL scores were observed in patients treated with oral DMTs compared to injectables or infusions. Discussion: The efficacy of DMT is a significant predictor of overall satisfaction. Quality of life has a minimal impact on overall satisfaction. EDSS, treatment duration and fatigue (MFIS) were not significant predictors of satisfaction outcomes. The knowledge provided by the PROs allows healthcare professionals to better understand the preferences and needs of PwMS, adjusting therapeutic strategies, improving patient experience and treatment effectiveness.

Indexed as

disease-modifying treatmentfatiguepatient- reported outcomesquality of liferelapsing remitting multiple sclerosistreatment satisfaction

Identifiers

PMID40135114
PMCPMC11934880

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.