ArticleJournal of cosmetic dermatology2025
Clinical Efficacy of CGF Combined With Periodic Supramolecular Salicylic Acid in the Treatment of Chloasma.
Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
objectiveTo investigate the clinical efficacy of CGF combined with supramolecular salicylic acid cycle injection for melasma.
methodsTwenty patients with chloasma admitted to our hospital were selected and treated with CGF facial injection. After each CGF injection, supramolecular salicylic acid was given once. After one cycle of treatment, the severity of melasma and skin parameters before and after treatment were compared using the modified melasma Area and Severity index (MASI) and VISIA facial image analysis system, respectively. At the same time, the patients' self-satisfaction was investigated.
resultsThe total effective rate of CGF combined with supramolecular salicylic acid in the treatment of chloasma was 95%. Compared with before treatment, the VISIA scores in spots, UV spots, brown spots, red areas, wrinkles, texture, pore and porphyrins scores were significantly increased after treatment. After CGF combined with supramolecular salicylic acid treatment, the MASI score of chloasma patients was significantly reduced (4.70 ± 2.47 vs. 15.30 ± 4.01, p < 0.001). The results showed that the total satisfaction of patients with facial skin improvement after CGF combined with supramolecular salicylic acid treatment was 95.00%.
conclusionCGF combined with supramolecular salicylic acid has an obvious effect on the comprehensive overall improvement of melasma and facial aging patients, and can effectively accelerate the speed of skin lesion repair and pigment elimination, which is worthy of clinical promotion and application.
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