Evidence map›Paper›PMID 40136392›Full record

ReviewCurrent issues in molecular biology2025

From Molecular to Clinical Implications of Sleep-Related Breathing Disorders on the Treatment and Recovery of Acute Stroke: A Scoping Review.

Karol Uscamaita, Olga Parra Ordaz, Imán Yazbeck Morell, Marta García Pla, María-José Sánchez-López, Adrià Arboix

Abstract readReview
In one paragraph

Review in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Karol UscamaitaNeurology Service, Sleep Disorders Unit, Hospital Universitari Sagrat Cor, Grupo Quirónsalud, 08029 Barcelona, Spain.ORCID 0000-0003-4846-8959
Olga Parra OrdazMedicine Department, University of Barcelona, 08036 Barcelona, Spain.
Imán Yazbeck MorellDepartment of Internal Medicine, Hospital Universitari Sagrat Cor, Grupo Quirónsalud, 08029 Barcelona, Spain.
Marta García PlaEmergency Department, Hospital Universitari Sagrat Cor, Grupo Quirónsalud, 08029 Barcelona, Spain.
María-José Sánchez-LópezMedical Library, Hospital Universitari Sagrat Cor, Grupo Quirónsalud, 08029 Barcelona, Spain.ORCID 0000-0002-3835-1223
Adrià ArboixCerebrovascular Division, Department of Neurology, Hospital Universitari Sagrat Cor, Grupo Quirónsalud, Universitat de Barcelona, 08029 Barcelona, Spain.ORCID 0000-0002-8512-7881

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The aim of this review is to map research into the molecular mechanisms linking sleep-related breathing disorders (SRBDs) and acute stroke and their clinical and therapeutic implications and to identify existing knowledge gaps to suggest new areas of research. (2) Methods: This review was conducted according to the PRISMA extension for scoping reviews (PRISMA-ScR) and a predetermined protocol shared among all authors. (3) Results: The review of the thirteen studies analyzed provides a focused view of the molecular features about interaction between obstructive sleep apnea (OSA) and acute stroke. Our review identifies and highlights the biomarkers most frequently found to be associated with acute stroke, SRBDs, and their clinical repercussions. (4) Conclusions: The association between the presence of sleep apnea, especially in its severe form, and elevated levels of inflammatory markers in patients with acute stroke is highlighted and new research topics in this area are proposed.

Indexed as

CPAPischemic strokepathophysiologysleep apneastroke

Identifiers

PMID40136392
PMCPMC11941448

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.