Evidence mapPaperPMID 40136669Full record

ArticleCells2025

Diallyl Trisulfide Attenuates Ischemia-Reperfusion-Induced ER Stress and Kidney Dysfunction in Aged Female Mice.

Sathnur Pushpakumar, Subir Kumar Juin, Hebah Almarshood, Dibson Dibe Gondim, Rosemary Ouseph, Utpal Sen

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sathnur PushpakumarDepartment of Physiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Subir Kumar JuinDepartment of Microbiology and Immunology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Hebah AlmarshoodDepartment of Physiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Dibson Dibe GondimDepartment of Pathology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Rosemary OusephDivision of Nephrology & Hypertension, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Utpal SenDepartment of Physiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.ORCID 0000-0002-0600-3443

Funding

miRNA Mechanism of Acute Kidney Injury in AgingR01DK116591 · NIDDK · UNIVERSITY OF LOUISVILLE · PI Utpal Sen, Suresh C. Tyagi · 2021 to 2021
$545k
NIDDK NIH HHS DK116591NIDDK NIH HHS R01 DK116591NIH HHS 1R01DK116591-06A1
6 · The paper itself

Abstract

Ischemia-reperfusion injury (IRI) is a common cause of acute kidney injury (AKI) in the aging population. Gender studies show that aging is associated with loss of protection from AKI in the female population. While ER stress contributes to IRI-induced AKI in the young, ER regulation during IR in the aged kidney is unclear. Because current evidence suggests hydrogen sulfide (H

Indexed as

Acute Kidney InjuryAgingAllyl CompoundsEndoplasmic Reticulum StressKidneyReperfusion InjurySulfidesAnimalsFemaleFibrosisMiceMice, Inbred C57BLSignal TransductionAllyl Compoundsdiallyl trisulfideSulfidesangiogenesisER stressH2Sischemia-reperfusionkidney injurysignaling

Identifiers

PMID40136669
PMCPMC11941362

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.