Evidence map›Paper›PMID 40136817›Full record

ArticleBiomimetics (Basel, Switzerland)2025

Smart Bio-Nanocoatings with Simple Post-Synthesis Reversible Adjustment.

Mikhail Kryuchkov, Zhehui Wang, Jana Valnohova, Vladimir Savitsky, Mirza Karamehmedović, Marc Jobin, Vladimir L Katanaev

Abstract read
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Advances in Biomimetics: Patents from Nature.Biomimetics (Basel, Switzerland) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mikhail KryuchkovDepartment of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Rue Michel Servet 1, CH-1211 Geneva, Switzerland.ORCID 0000-0002-7141-2964
Zhehui WangSchool of Chemistry and Pharmaceutical Engineering, Shandong First Medical University (Shandong Academy of Medical Sciences), Tai'an 271016, China.
Jana ValnohovaDepartment of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Rue Michel Servet 1, CH-1211 Geneva, Switzerland.
Vladimir SavitskyZoological Museum, Moscow Lomonosov State University, Bol'shaya Nikitskaya Street 2, Moscow 125009, Russia.ORCID 0000-0002-6680-754X
Mirza KaramehmedovićDepartment of Applied Mathematics and Computer Science, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark.ORCID 0000-0003-0038-9020
Marc JobinHaute ecole du Paysage, D'ingenierie et D'architecture de Geneve, University of Applied Sciences of Western Switzerland (HES-SO), 4 Rue de la Prairie, CH-1202 Geneva, Switzerland.
Vladimir L KatanaevDepartment of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Rue Michel Servet 1, CH-1211 Geneva, Switzerland.ORCID 0000-0002-7909-5617

Funding

National Natural Science Foundation of China 32350410406Swiss National Science Foundation 10.003.592
6 · The paper itself

Abstract

Nanopatterning of signal-transmitting proteins is essential for cell physiology and drug delivery but faces challenges such as high cost, limited pattern variability, and non-biofriendly materials. Arthropods, particularly beetles (Coleoptera), offer a natural model for biomimetic nanopatterning due to their diverse corneal nanostructures. Using atomic force microscopy (AFM), we analyzed Coleoptera corneal nanocoatings and identified dimpled nanostructures that can transform into maze-like/nipple-like protrusions. Further analysis suggested that these modifications result from a temporary, self-assembled process influenced by surface adhesion. We identified cuticular protein 7 (CP7) as a key component of dimpled nanocoatings. Biophysical analysis revealed CP7's unique self-assembly properties, allowing us to replicate its nanopatterning ability in vitro. Our findings demonstrate CP7's potential for bioinspired nanocoatings and provide insights into the evolutionary mechanisms of nanostructure formation. This research paves the way for cost-effective, biomimetic nanopatterning strategies with applications in nanotechnology and biomedicine.

Indexed as

active coatingantireflectivebio-mimeticeco-friendlyprotein-based coatingsself-assemblysmart materialsswitchable

Identifiers

PMID40136817
PMCPMC11940101

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.