ArticleJournal of cardiovascular development and disease2025
Prevalence and Correlates of Dilated and Non-Dilated Left Ventricular Cardiomyopathy in Transfusion-Dependent Thalassemia: Data from a National, Multicenter, Observational Registry.
Antonella Meloni, Laura Pistoia, Anna Spasiano, Francesco Sorrentino, Giuseppe Messina, Michele Santodirocco, Zelia Borsellino, Valerio Cecinati, Vincenzo Positano, Gennaro Restaino and 6 more
Abstract read
In one paragraphArticle in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
16 authors.
Antonella MeloniBioengineering Unit, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.ORCID 0000-0002-2284-8585 Laura PistoiaUnità Operativa Semplice Dipartimentale Ricerca Clinica, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.ORCID 0000-0002-5319-2769 Anna SpasianoUnità Operativa Semplice Dipartimentale Malattie Rare del Globulo Rosso, Azienda Ospedaliera di Rilievo Nazionale "A. Cardarelli", 80131 Napoli, Italy.
Francesco SorrentinoUnità Operativa Semplice Dipartimentale Day Hospital Talassemici, Ospedale "Sant'Eugenio", 00143 Roma, Italy.
Giuseppe MessinaCentro Microcitemie, Grande Ospedale Metropolitano "Bianchi-Melacrino-Morelli", 89100 Reggio Calabria, Italy.
Michele SantodiroccoCentro Microcitemia-Day Hospital Thalassemia Poliambulatorio "Giovanni Paolo II", Istituto di Ricovero e Cura a Carattere Scientifico Ospedale Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy.ORCID 0000-0002-0032-5628 Zelia BorsellinoUnità Operativa Complessa Ematologia con Talassemia, Azienda di Rilievo Nazionale ad Alta Specializzazione Civico "Benfratelli-Di Cristina", 90134 Palermo, Italy.
Valerio CecinatiStruttura Semplice di Microcitemia, Ospedale "SS. Annunziata", 74123 Taranto, Italy.
Vincenzo PositanoBioengineering Unit, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.ORCID 0000-0001-6955-9572 Nicolò SchicchiDipartimento di Radiologia, Azienda Ospedaliero-Universitaria Ospedali Riuniti "Umberto I-Lancisi-Salesi", 60020 Ancona, Italy.
Emanuele GrassedonioSezione di Scienze Radiologiche-Dipartimento di Biopatologia e Biotecnologie Mediche, Policlinico "Paolo Giaccone", 90127 Palermo, Italy.ORCID 0000-0002-2113-7300 Antonino ValloneReparto di Radiologia, Azienda Ospedaliera "Garibaldi" Presidio Ospedaliero Nesima, 95126 Catania, Italy.
Michele EmdinCardiology and Cardiovascular Medicine, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.
Alberto ClementeDepartment of Radiology, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.ORCID 0000-0002-4285-9468 Andrea BarisonCardiology and Cardiovascular Medicine, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.ORCID 0000-0001-9042-340X Funding
The MIOT project received "no-profit support" from industrial sponsorships (Chiesi Farmaceutici S.p.A. and ApoPharma Inc.). The funders had no role in study design, data collection and anal-ysis, decision to publish, or preparation of the manuscript na
6 · The paper itselfAbstract
We investigated the prevalence, clinical characteristics, and prognostic role of dilated cardiomyopathy (DCM) and non-dilated left ventricular cardiomyopathy (NDLVC) in patients with transfusion-dependent β-thalassemia (β-TDT). We retrospectively included 415 β-TDT patients who underwent cardiovascular magnetic resonance to quantify myocardial iron overload (MIO) and biventricular function parameters and to detect replacement myocardial fibrosis. Demographic and laboratory parameters were comparable among patients with no overt cardiomyopathy (NOCM;
Indexed as
cardiovascular magnetic resonancedilated cardiomyopathynon-dilated left ventricular cardiomyopathyprognosistransfusion-dependent β-thalassemia
Identifiers
PMID40137101
PMCPMC11943376
What Socratic holds
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