Evidence mapPaperPMID 40137302Full record

ReviewMarine drugs2025

Last Decade Insights in Exploiting Marine Microorganisms as Sources of New Bioactive Natural Products.

Costanza Ragozzino, Vincenza Casella, Alessandro Coppola, Silvia Scarpato, Carmine Buonocore, Antonella Consiglio, Fortunato Palma Esposito, Christian Galasso, Pietro Tedesco, Gerardo Della Sala and 3 more

Abstract readReview
In one paragraph

Review in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Bioactive Furan Derivatives fromCurrent drug discovery technologies · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Costanza RagozzinoDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via Ammiraglio, Ferdinando Acton 55, 80133 Naples, Italy.
Vincenza CasellaDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via Ammiraglio, Ferdinando Acton 55, 80133 Naples, Italy.
Alessandro CoppolaDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via Ammiraglio, Ferdinando Acton 55, 80133 Naples, Italy.
Silvia ScarpatoDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via Ammiraglio, Ferdinando Acton 55, 80133 Naples, Italy.
Carmine BuonocoreDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via Ammiraglio, Ferdinando Acton 55, 80133 Naples, Italy.ORCID 0000-0002-8327-954X
Antonella ConsiglioDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via Ammiraglio, Ferdinando Acton 55, 80133 Naples, Italy.ORCID 0009-0002-3472-2493
Fortunato Palma EspositoDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via Ammiraglio, Ferdinando Acton 55, 80133 Naples, Italy.ORCID 0000-0002-3768-4712
Christian GalassoDepartment of Ecosustainable Marine Biotechnology, Calabria Marine Centre, CRIMAC, Stazione Zoologica Anton Dohrn, C. da Torre Spaccata, 87071 Amendolara, Italy.ORCID 0000-0002-1262-959X
Pietro TedescoDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via Ammiraglio, Ferdinando Acton 55, 80133 Naples, Italy.ORCID 0000-0003-0165-5386
Gerardo Della SalaDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via Ammiraglio, Ferdinando Acton 55, 80133 Naples, Italy.ORCID 0000-0001-8957-3259
Donatella de PascaleDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via Ammiraglio, Ferdinando Acton 55, 80133 Naples, Italy.
Laura VitaleDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via Ammiraglio, Ferdinando Acton 55, 80133 Naples, Italy.ORCID 0000-0003-2831-1794
Daniela CoppolaDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via Ammiraglio, Ferdinando Acton 55, 80133 Naples, Italy.ORCID 0000-0001-6699-8967

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marine microorganisms have emerged as prolific sources of bioactive natural products, offering a large chemical diversity and a broad spectrum of biological activities. Over the past decade, significant progress has been made in discovering and characterizing these compounds, pushed by technological innovations in genomics, metabolomics, and bioinformatics. Furthermore, innovative isolation and cultivation approaches have improved the isolation of rare and difficult-to-culture marine microbes, leading to the identification of novel secondary metabolites. Advances in synthetic biology and metabolic engineering have further optimized natural product yields and the generation of novel compounds with improved bioactive properties. This review highlights key developments in the exploitation of marine bacteria, fungi, and microalgae for the discovery of novel natural products with potential applications in diverse fields, underscoring the immense potential of marine microorganisms in the growing Blue Economy sector.

Indexed as

Aquatic OrganismsBacteriaBiological ProductsAnimalsDrug DiscoveryFungiHumansMetabolic EngineeringMicroalgaeBiological Productsbioactivitybioinformatic toolsbiotechnological applicationsco-cultivationhigh-throughput screeningmarine microorganismsmetabologenomicsnatural productsOSMAC

Identifiers

PMID40137302
PMCPMC11943599

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.