Evidence map›Paper›PMID 40137480›Full record

ArticleToxics2025

Biomonitoring of Serum Inorganic Element Concentrations in Morbidly Obese Patients: Impact of Bariatric Surgery.

Álvaro Ramos-Luzardo, Pilar Fernández Valerón, Beatriz Vanessa Díaz-González, Manuel Zumbado, Katherine Simbaña-Rivera, Inmaculada Bautista-Castaño, Norberto Ruiz-Suárez, Elisabeth Hernández-García, Judith Cornejo-Torre, Octavio P Luzardo and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Álvaro Ramos-LuzardoDepartment of Biochemistry and Molecular Biology, Physiology, Genetics, and Immunology, Universidad de Las Palmas de Gran Canaria, 35016 Las Palmas de Gran Canaria, Spain.ORCID 0009-0002-9435-2228
Pilar Fernández ValerónDepartment of Biochemistry and Molecular Biology, Physiology, Genetics, and Immunology, Universidad de Las Palmas de Gran Canaria, 35016 Las Palmas de Gran Canaria, Spain.ORCID 0000-0001-5865-7003
Beatriz Vanessa Díaz-GonzálezResearch Institute of Biomedical and Health Sciences (IUIBS), Universidad de Las Palmas de Gran Canaria, 35016 Las Palmas de Gran Canaria, Spain.ORCID 0009-0009-9500-3581
Manuel ZumbadoToxicology Unit, Clinical Sciences Department, Universidad de Las Palmas de Gran Canaria, 35016 Las Palmas de Gran Canaria, Spain.ORCID 0000-0002-1534-7758
Katherine Simbaña-RiveraToxicology Unit, Clinical Sciences Department, Universidad de Las Palmas de Gran Canaria, 35016 Las Palmas de Gran Canaria, Spain.ORCID 0000-0002-8130-5361
Inmaculada Bautista-CastañoCentro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0001-9257-8739
Norberto Ruiz-SuárezToxicology Unit, Clinical Sciences Department, Universidad de Las Palmas de Gran Canaria, 35016 Las Palmas de Gran Canaria, Spain.ORCID 0000-0003-3610-8403
Elisabeth Hernández-GarcíaResearch Institute of Biomedical and Health Sciences (IUIBS), Universidad de Las Palmas de Gran Canaria, 35016 Las Palmas de Gran Canaria, Spain.
Judith Cornejo-TorreResearch Institute of Biomedical and Health Sciences (IUIBS), Universidad de Las Palmas de Gran Canaria, 35016 Las Palmas de Gran Canaria, Spain.
Octavio P LuzardoToxicology Unit, Clinical Sciences Department, Universidad de Las Palmas de Gran Canaria, 35016 Las Palmas de Gran Canaria, Spain.
Lluis Serra-MajemResearch Institute of Biomedical and Health Sciences (IUIBS), Universidad de Las Palmas de Gran Canaria, 35016 Las Palmas de Gran Canaria, Spain.ORCID 0000-0002-9658-9061
Luis Alberto Henríquez-HernándezToxicology Unit, Clinical Sciences Department, Universidad de Las Palmas de Gran Canaria, 35016 Las Palmas de Gran Canaria, Spain.ORCID 0000-0003-3237-0316

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose tissue, in addition to serving as energy storage, can store lipophilic substances, some of which may pose a health risk if massively mobilized during rapid weight loss. This study aimed to biomonitor inorganic elements in obese patients undergoing bariatric surgery and analyze the role of sociodemographic factors. ICP-MS was employed to quantify 55 elements, including elements identified from the ATSDR's Substance Priority List and rare-earth elements, in serum samples of 58 obese patients before and after bariatric surgery. A total of 39 out of 55 elements were detected, either before or after surgery, in at least one patient. Serum concentrations of gold, copper, mercury, platinum, and selenium significantly decreased after surgery. Serum concentrations of iron and zinc were significantly lower before surgery. Age, sex, diabetes status, arterial hypertension, and family history of obesity were demographic factors associated with the concentration of elements. Correlation analyses showed significant associations between elements and total lipid concentration or body mass index. Our findings indicate a complex interplay between inorganic elements and body fat and provide relevant information regarding the biomonitoring of these chemical elements in a specific and understudied population.

Indexed as

bariatric surgeryheavy metalsinorganic elementsobesityobesogensrare-earth elementsweight loss

Identifiers

PMID40137480
PMCPMC11945562

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.