Evidence map›Paper›PMID 40137520›Full record

ArticleToxics2025

The Neurobehavioral Impact of Zinc Chloride Exposure in Zebrafish: Evaluating Cognitive Deficits and Probiotic Modulation.

Madalina Ene, Alexandra Savuca, Alin-Stelian Ciobica, Roxana Jijie, Irina Luciana Gurzu, Luminita Diana Hritcu, Ionut-Alexandru Chelaru, Gabriel-Ionut Plavan, Mircea Nicusor Nicoara, Bogdan Gurzu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Madalina EneDepartment of Biology, Faculty of Biology, "Alexandru Ioan Cuza" University of Iasi, Carol I Avenue, 20A, 700505 Iasi, Romania.
Alexandra SavucaDoctoral School of Geosciences, Faculty of Geography and Geology, "Alexandru Ioan Cuza" University of Iasi, Carol I Avenue, 20A, 700505 Iasi, Romania.ORCID 0000-0003-2030-1436
Alin-Stelian CiobicaDepartment of Biology, Faculty of Biology, "Alexandru Ioan Cuza" University of Iasi, Carol I Avenue, 20A, 700505 Iasi, Romania.
Roxana JijieResearch Center on Advanced Materials and Technologies, Department of Exact and Natural Sciences, Institute of Interdisciplinary Research, "Alexandru Ioan Cuza" University of Iasi, 700506 Iasi, Romania.ORCID 0000-0003-0354-943X
Irina Luciana GurzuDepartment of Preventive Medicine and Interdisciplinarity, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 16th Universitatii Street, 700115 Iasi, Romania.ORCID 0000-0003-3095-3497
Luminita Diana HritcuInternal Medicine Clinic, "Ion Ionescu de la Brad" University of Life Sciences, Sadoveanu Alley No. 3, 700490 Iasi, Romania.
Ionut-Alexandru ChelaruDoctoral School of Geosciences, Faculty of Geography and Geology, "Alexandru Ioan Cuza" University of Iasi, Carol I Avenue, 20A, 700505 Iasi, Romania.ORCID 0009-0000-0383-1799
Gabriel-Ionut PlavanDepartment of Biology, Faculty of Biology, "Alexandru Ioan Cuza" University of Iasi, Carol I Avenue, 20A, 700505 Iasi, Romania.ORCID 0000-0002-1194-1768
Mircea Nicusor NicoaraDepartment of Biology, Faculty of Biology, "Alexandru Ioan Cuza" University of Iasi, Carol I Avenue, 20A, 700505 Iasi, Romania.ORCID 0000-0002-9755-6771
Bogdan GurzuDepartment of Morfofunctional Sciences, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 16th Universitatii Street, 700115 Iasi, Romania.ORCID 0000-0002-1834-9142

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc contamination in aquatic environments has become a growing concern due to its potential to bioaccumulate and induce neurotoxic effects in aquatic organisms. As an essential trace element, zinc plays a crucial role in various physiological processes, but excessive exposure can disrupt the gut-brain axis, leading to cognitive and behavioral impairments. Recent studies have suggested that probiotics may offer protective effects against environmental neurotoxins by modulating the gut microbiota and associated neurological functions. The zebrafish (

Indexed as

behaviorprobioticstoxicityzebrafishzinc chloride

Identifiers

PMID40137520
PMCPMC11945970

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.