Evidence map›Paper›PMID 40138213›Full record

ArticleJournal of synchrotron radiation2025

Macromolecular crystallography at Elettra: current and future perspectives.

Raghurama P Hegde, Nicola Demitri, Annie Héroux, Alessandro Olivo, Giorgio Bais, Michele Cianci, Paola Storici, Dan George Dumitrescu, Nishant Kumar Varshney, Balasubramanian Gopal and 4 more

Erratum issuedAbstract read
In one paragraph

Article in Journal of synchrotron radiation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Raghurama P HegdeElettra - Sincrotrone Trieste SCpA, SS 14 km 163,5 in AREA Science Park, Basovizza, 34149 Trieste, Italy.ORCID 0000-0003-2713-6904
Nicola DemitriElettra - Sincrotrone Trieste SCpA, SS 14 km 163,5 in AREA Science Park, Basovizza, 34149 Trieste, Italy.ORCID 0000-0003-0288-3233
Annie HérouxFormer Elettra - Sincrotrone Trieste SCpA, SS 14 km 163,5 in AREA Science Park, Basovizza, 34149 Trieste, Italy.ORCID 0000-0001-5713-0525
Alessandro OlivoElettra - Sincrotrone Trieste SCpA, SS 14 km 163,5 in AREA Science Park, Basovizza, 34149 Trieste, Italy.ORCID 0000-0002-2610-7274
Giorgio BaisElettra - Sincrotrone Trieste SCpA, SS 14 km 163,5 in AREA Science Park, Basovizza, 34149 Trieste, Italy.ORCID 0000-0002-6576-3426
Michele CianciDepartment of Agricultural, Food and Environmental Sciences, Università Politecnica delle Marche, via Brecce Bianche 10, 60131 Ancona, Italy.ORCID 0000-0001-5607-6061
Paola StoriciElettra - Sincrotrone Trieste SCpA, SS 14 km 163,5 in AREA Science Park, Basovizza, 34149 Trieste, Italy.ORCID 0000-0002-2590-3332
Dan George DumitrescuNobian, Van Asch v. Wijckstraat 53, 3811 LP Amersfoort, The Netherlands.ORCID 0000-0002-2074-4870
Nishant Kumar VarshneyIR Technology Services Pvt Ltd, EL-91, TTC Industrial Area, Electronic Zone, Mahape, Navi Mumbai, Maharashtra 400710, India.ORCID 0000-0003-0808-5144
Balasubramanian GopalMolecular Biophysics Unit, Division of Biological Sciences, Indian Institute of Science, Bengaluru 560012, India.ORCID 0000-0001-9097-5052
D D SarmaSolid State and Structural Chemistry Unit, Indian Institute of Science, Bengaluru 560012, India.ORCID 0000-0001-6433-1069
Lisa VaccariElettra - Sincrotrone Trieste SCpA, SS 14 km 163,5 in AREA Science Park, Basovizza, 34149 Trieste, Italy.ORCID 0000-0003-2355-114X
Silvia OnestiElettra - Sincrotrone Trieste SCpA, SS 14 km 163,5 in AREA Science Park, Basovizza, 34149 Trieste, Italy.
Maurizio PolentaruttiElettra - Sincrotrone Trieste SCpA, SS 14 km 163,5 in AREA Science Park, Basovizza, 34149 Trieste, Italy.ORCID 0000-0001-7385-3045

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Elettra synchrotron radiation facility, located in Trieste, Italy, is a third-generation storage ring, operating in top-up mode at both 2.0 and 2.4 GeV. The facility currently hosts one beamline fully dedicated to macromolecular crystallography, XRD2. XRD2 is based on a superconducting wiggler, and it has been open to users since 2018. On-site and remote access for data collection, as well as monitoring tools and automatic data analysis pipelines are available to its users. In addition, since 1994 Elettra has operated a general-purpose diffraction beamline, XRD1, offering the macromolecular community a wide spectrum extending to long wavelengths for phasing and ion identification. Ancillary facilities support the beamlines, providing sample preparation and a high-throughput crystallization platform for the user community. A new CryoEM facility is being established on campus and jointly operated by the Consiglio Nazionale della Ricerche - Istituto Officina dei Materiali (CNR-IOM) and Elettra, providing further opportunities to the Elettra user community. This review outlines the current capabilities and anticipated developments for macromolecular crystallography at Elettra to accompany the upcoming upgrade to Elettra 2.0, featuring a six-bend enhanced achromat lattice. The new source is expected to deliver a high-brilliance beam, enabling the macromolecular crystallography community to better address the emerging and future scientific challenges.

Indexed as

data collectionElettra upgrademacromolecular crystallographyX-ray diffraction

Identifiers

PMID40138213
PMCPMC12067329

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.