Evidence map›Paper›PMID 40140013›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

Analysis of the correlation between ABO blood type and three bone mineral density measurements in patients with lumbar degenerative diseases.

Yongdi Wang, Youwei Ai, Qian Chen, Juehan Wang, Hong Ding, Dun Luo, Zhuojie Xiao, Ce Zhu, Limin Liu

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

9 authors.

Yongdi WangDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Youwei AiDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Qian ChenDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Juehan WangUniversity of Hong Kong, Hong Kong, China.
Hong DingDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Dun LuoDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Zhuojie XiaoDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Ce ZhuDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China. zhuce0322@126.com.
Limin LiuDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China. liulimin_spine@163.com.

Funding

National Key R&D Program of China 2023YFC2507700/2023YFC2507701Sichuan Provincial Medical Association Special Research Fund 2023SAT06Sichuan Science and Technology Program (2024NSFSC1816);Projects of the Science and Technology Department of Sichuan Province 2024NSFSC1816the 1·3·5 project for disciplines of excellence Clinical Research Incubation Project, West China Hospital, Sichuan University 2021HXFH003
6 · The paper itself

Abstract

purposeThe purpose of this study is to evaluate the association between ABO blood type and three bone mineral density (BMD) measurements including CT Hounsfield units (HU), vertebral bone quality (VBQ) scores, and Dual-energy x-ray absorptiometry (DEXA) in patients undergoing transforaminal lumbar interbody fusion (TLIF) for lumbar degenerative diseases (LDD) and determine the postoperative BMD-related complications and patient-reported outcomes in four ABO-type groups.

methodsThis study included patients undergoing single-level TLIF for LDD at our center from 2014 to 2020. Demographic and clinical information were collected. The correlation between ABO blood type and three BMD measurements was analyzed. Radiographic images, the visual analog scale (VAS) score of back and leg pain, and the Oswestry Disability Index (ODI) were used to compare the differences in BMD-related complications and patient-reported outcomes between four ABO-type groups.

results350 patients were included in this study. ABO blood group distribution is O (33.7%), A (32.6%), B (24.6%), and AB (9.7%). The values of CT HU in four groups have a significant difference (P = 0.001). Patients with CT HU ≤ 110 were older (62.6 ± 11.6 vs. 58.4 ± 13.4, P = 0.022) and had a higher proportion of O blood type (45.2% vs. 31.3%) compared to patients with CT HU>110. There are no statistically significant differences in BMD-related complications and patient-reported outcomes between the four ABO-type groups.

conclusionOur study found a close connection between ABO blood type and CT HU in patients undergoing TLIF for LDD and determined O blood type is a risk factor for osteoporosis.

Indexed as

ABO Blood-Group SystemBone DensityIntervertebral Disc DegenerationLumbar VertebraeAbsorptiometry, PhotonAdultAgedFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesSpinal FusionTomography, X-Ray ComputedABO Blood-Group SystemABO blood typeBone mineral densityPostoperative complicationsTLIF

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.