ArticleScientific reports2025
Investigating the link between oral health conditions and systemic diseases: A cross-sectional analysis.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association of frailty and mortality risk in community-dwelling older adults: a systematic review and meta-analysis of 59 international prospective cohort studies.BMC public health · 2026Pooled it
- Association of periodontal disease with risk atrial fibrillation: systematic review.BMC oral health · 2025Pooled it
- In vivo exposure to cranberry juice suppresses dental plaque regrowth and acid production in adults and children: a PGRM study.Scientific reports · 2026Trial
- Association between Decayed, Missing, Filled Teeth (DMFT) index and diabetes mellitus among adults in Central Sudan: a community-based cross-sectional study.The Libyan journal of medicine · 2026Article
- Pharmacists' role in recognising medication-related oral health risks in aged care: a qualitative study of pharmacists' and dentists' perspectives.International journal of clinical pharmacy · 2026Article
- Association of Subjective Oral Status and Oral Health Behaviours With a History of Systemic Disease Among Community-Dwelling Older Adults.Oral health & preventive dentistry · 2026Article
- Article
- Hypoxia Exacerbates Periapical Periodontitis-Associated Pathological Bone Loss via the Hypoxia-Inducible Factor-2α-Calmodulin-Dependent Protein Kinase IV Axis.Cell proliferation · 2026Article
- Role of β-adrenergic signaling in the development of Porphyromonas gingivalis lipopolysaccharide-induced cardiac dysfunction in mice.Scientific reports · 2026Article
- Epidemiology and risk factors of stroke in the Americas: a comprehensive narrative literature review.Lancet regional health. Americas · 2026Review
- Systemic Inflammatory and Hematologic Biomarkers in Pediatric Dental Caries: Clear Group Differences with Limited Independent Association with DMFT.Journal of clinical medicine · 2026Article
- The Promise and Challenges of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Periodontal Disease.Pathogens (Basel, Switzerland) · 2026Review
- Oral Health Management in Pediatric Surgical Inpatients: Development of Clinical Protocols Based on a Prospective Observational Study.Dentistry journal · 2026Article
- The relationship between oral health and active aging among the elderly in rural China: the chain mediating effect of intergenerational support and social isolation.BMC geriatrics · 2026Article
- Associations Between Comorbidities, Medication Use and Dental Outcomes in Clinical Practice in Hail Dental Centre in Saudi Arabia: A Retrospective Study.Oral health & preventive dentistry · 2026Article
- The Microbial Mechanisms of Cardiovascular Disease: Oral Dysbiosis as a Systemic Instigator.Journal of cardiovascular translational research · 2026Review
- Review
- Osteoimmunologic and Immune-Aging Signatures in Postmenopausal Women with Periodontitis and Low Bone Mineral Density: A Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2026Article
- Value of Oral Health Assessments for Older People with Memory Complaints Visiting a Memory Clinic for a Comprehensive Geriatric Assessment: A Cross-Sectional Study.International journal of environmental research and public health · 2026Article
- Emerging Role of the NLRP3 Inflammasome in the Onset of Oral Diseases and Its Potential as a Therapeutic Target.International journal of molecular sciences · 2026Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigates the association between oral health issues, specifically periodontitis and dental caries, and systemic health conditions such as diabetes and hypertension. The goal is to determine the strength of these associations using statistical analysis. We conducted a cross-sectional study utilizing the National Health and Nutrition Examination Survey (NHANES) data from 2017-2020, focusing on 13,772 adults with complete data on oral and systemic health variables. Oral health indicators were periodontitis and dental caries, while systemic health variables included diabetes and hypertension. The statistical analysis involved Cramer's V to assess the strength of associations between these health conditions. The study found statistically significant associations between oral and systemic health conditions. There was a moderate association between periodontitis and diabetes (Cramer's V = 0.14) and a moderate association between dental caries and hypertension (Cramer's V = 0.12). The results underscore the interconnected nature of oral and systemic health, suggesting that poor oral health can be an indicator of broader health issues. These associations could guide integrated health care strategies, emphasizing the need for dental health evaluations in patients with diabetes and hypertension.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.