ArticleNPJ science of food2025
Multiomics reveals the molecular mechanism of unsaturated fatty acid-induced terpenoid biosynthesis in Sanghuangporus lonicericola.
Article in NPJ science of food, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- A Study on the Analysis of Microbial Community Characteristics and the Regulation of Safety and Flavor Composition in Homemade Fermented Chili Peppers via Ultrasound-Assisted Fermentation.Journal of food science · 2026Article
- Comparative mitochondrial genome analyses of five medicinal mushroom Sanghuangporus provide insights into conservation, variation, and phylogenetic relationships.BMC genomics · 2026Article
- Fungal-fungal interaction between Sanghuangporus vaninii and its endophytic Fusarium solani rewires host secondary metabolism to boost bioactive metabolite production.Microbial cell factories · 2026Article
- Integrated GC-MS and UPLC-Q-Orbitrap MS untargeted metabolomics for the comprehensive identification of metabolites and characterization of metabolic pathways in key tissues ofFood chemistry: X · 2026Article
- Integrative phytochemical profiling andFrontiers in nutrition · 2026Article
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Authors and funding
15 authors.
Funding
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Abstract
Treatment with C18:1 and C18:2, but not C18:0, increased the triterpenoid content of the medicinal fungus Sanghuangporus lonicericola. We identified 413 terpenoids, including 210 volatile terpenoids. Eight upregulated terpenoids, including 3,13,15-trihydroxyoleanane-12-one, dulcioic acid and serrat-14-ene-3,20,24,29-tetrol, were shared between the C18:1 and C18:2 treatments but not the C18:0 treatment. The C18:1 and C18:2 treatments increased the levels of 12 and 7 odour-related terpenoids, respectively, and increased the level of alpha-farnesene (herbal odour). Gene set enrichment analysis revealed that compared with C18:0, C18:1 and C18:2 produced stronger activation of the terpenoid biosynthesis, fatty acid degradation, and MAPK signalling pathways and stronger inhibition of basal transcription factors at both the transcript and protein levels. Finally, two-way orthogonal partial least squares analysis revealed that gene and protein expression in the identified pathways was correlated with levels of unsaturated fatty acid-induced terpenoid metabolites. Together, our integrated multiomics data revealed the key pathways involved in unsaturated fatty acid-induced terpenoid biosynthesis in S. lonicericola.
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