Evidence map›Paper›PMID 40140782›Full record

ArticleBMC gastroenterology2025

Association between atherogenic index of plasma and chronic diarrhea: a cross-sectional study of the NHANES 2005-2010.

Rongpeng Chen, Zexin Fu, Zhicheng Feng, Feng Xiao, Guoqiang Wang

Abstract read
In one paragraph

Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rongpeng ChenDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Guangzhou Medical University, 250 Changgang East Road, Haizhu District, Guangzhou, 510260, China.
Zexin FuThe Second Clinical College, Guangzhou Medical University, 1 Xinzao Road, Panyu District, Guangzhou, 511436, China.
Zhicheng FengDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Guangzhou Medical University, 250 Changgang East Road, Haizhu District, Guangzhou, 510260, China.
Feng XiaoDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Guangzhou Medical University, 250 Changgang East Road, Haizhu District, Guangzhou, 510260, China.
Guoqiang WangDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Guangzhou Medical University, 250 Changgang East Road, Haizhu District, Guangzhou, 510260, China. wgqjyh@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic diarrhea (CD), a common chronic condition resulting from various mechanisms, has chronic inflammation as a primary determinant. Despite recent research exploring the potential mechanisms linking lipids and diarrhea, clinical studies on the relationship between lipids and the onset of CD are limited. This study aimed to investigate the association between the atherogenic index of plasma (AIP) and CD risk.

methodsThis cross-sectional study used data from the 2005-2010 NHANES. The association between AIP and CD was examined through multiple linear regression analyses. A smooth curve-fitting algorithm was applied to assess the potential non-linear dose-response relationship between AIP and CD, and subgroup analyses were conducted.

resultsAmong 5,948 participants, 440 (7.4%) had CD. After adjusting for potential confounders, AIP was significantly associated with CD (OR, 1.57; 95% CI, 1.08-2.30; P = 0.018). The highest AIP quartile (Q4; 0.18 to 0.92) showed an adjusted OR for CD of 1.51 (95% CI, 1.10-2.07; P = 0.011) versus the lowest quartile (Q1; -1.15 to -0.25). Subgroup analyses indicated that diabetic individuals with higher AIP had a higher CD risk (OR, 3.84; 95% CI, 1.45-10.15), with an observed additive interaction (P for interaction = 0.045).

conclusionsThis study demonstrates a significant association between AIP and CD risk. AIP may serve as a promising indicator for assessing CD risk, offering valuable insights for prevention and treatment strategies.

Indexed as

AtherosclerosisDiarrheaAdultAgedChronic DiseaseCross-Sectional StudiesFemaleHumansLinear ModelsMaleMiddle AgedNutrition SurveysRisk FactorsAtherogenic index of plasmaChronic diarrheaLipidNHANES

Identifiers

PMID40140782
PMCPMC11938632

What Socratic holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.