Evidence map›Paper›PMID 40140932›Full record

ArticleHead & face medicine2025

Deep learning based quantitative cervical vertebral maturation analysis.

Fulin Jiang, Abbas Ahmed Abdulqader, Yan Yan, Fangyuan Cheng, Tao Xiang, Jinghong Yu, Juan Li, Yong Qiu, Xin Chen

Abstract read
In one paragraph

Article in Head & face medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fulin JiangCollege of Computer Science, Chongqing University, Chongqing University Three Gorges Hospital, Chongqing, 400044, China.
Abbas Ahmed AbdulqaderState Key Laboratory of Oral Diseases, West China School of Stomatology, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.
Yan YanState Key Laboratory of Oral Diseases, West China School of Stomatology, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.
Fangyuan ChengChengdu Boltzmann Intelligence Technology Co., Ltd, Chengdu, 610095, China.
Tao XiangCollege of Computer Science, Chongqing University, Chongqing University Three Gorges Hospital, Chongqing, 400044, China.
Jinghong YuCollege of Computer Science, Chongqing University, Chongqing University Three Gorges Hospital, Chongqing, 400044, China.
Juan LiState Key Laboratory of Oral Diseases, West China School of Stomatology, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China. lijuan@scu.edu.cn.
Yong QiuCollege of Computer Science, Chongqing University, Chongqing University Three Gorges Hospital, Chongqing, 400044, China. qiuy@cqu.edu.cn.
Xin ChenCollege of Computer Science, Chongqing University, Chongqing University Three Gorges Hospital, Chongqing, 400044, China. chenxin@cqu.edu.cn.

Funding

Chongqing Wanzhou District PhD Direct-Acess Research Project wzstc20230409Chongqing Wanzhou District Science and Health Joint Medical wzstc-kw2022016
6 · The paper itself

Abstract

objectivesThis study aimed to enhance clinical diagnostics for quantitative cervical vertebral maturation (QCVM) staging with precise landmark localization. Existing methods are often subjective and time-consuming, while deep learning alternatives withstand the complex anatomical variations. Therefore, we designed an advanced two-stage convolutional neural network customized for improved accuracy in cervical vertebrae analysis.

methodsThis study analyzed 2100 cephalometric images. The data distribution to an 8:1:1 for training, validation, and testing. The CVnet system was designed as a two-step method with a comprehensive evaluation of various regions of interest (ROI) sizes to locate 19 cervical vertebral landmarks and classify precision maturation stages. The accuracy of landmark localization was assessed by success detection rate and student t-test. The QCVM diagnostic accuracy test was conducted to evaluate the assistant performances of our system for six junior orthodontists.

resultsUpon precise calibration with optimal ROI size, the landmark localization registered an average error of 0.66 ± 0.46 mm and a success detection rate of 98.10% within 2 mm. Additionally, the identification accuracy of QCVM stages was 69.52%, resulting in an enhancement of 10.95% in the staging accuracy of junior orthodontists in the diagnostic test.

conclusionsThis study presented a two-stage neural network that successfully automated the identification of cervical vertebral landmarks and the staging of QCVM. By streamlining the workflow and enhancing the accuracy of skeletal maturation estimation, this method offered valuable clinical support, particularly for practitioners with limited experience or access to advanced diagnostic resources, facilitating more consistent and reliable treatment planning.

Indexed as

Age Determination by SkeletonCephalometryCervical VertebraeDeep LearningAnatomic LandmarksChildFemaleHumansMaleNeural Networks, ComputerArtificial intelligenceAutomated landmark locationLateral cephalogramOrthodonticsQuantitative cervical vertebral maturation (QCVM)

Identifiers

PMID40140932
PMCPMC11938625

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.