Evidence map›Paper›PMID 40141065›Full record

ArticleInternational journal of molecular sciences2025

9-Hydroxyaristoquinolone: A New Indole Alkaloid Isolated from

Rebeca Pérez, Viviana Burgos, Jaime R Cabrera-Pardo, Leandro Ortiz, Antoni Camins, Miren Ettcheto, Bernd Schmidt, Vaderament-A Nchiozem-Ngnitedem, Cristian Paz

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Clinical Evidence on the Health Effects ofAntioxidants (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rebeca PérezLaboratory of Natural Products & Drug Discovery, Center CEBIM, Department of Basic Sciences, Faculty of Medicine, Universidad de La Frontera, Temuco 4780000, Chile.
Viviana BurgosEscuela de Tecnología Médica, Facultad de Salud, Universidad Santo Tomás, Temuco 4780000, Chile.
Jaime R Cabrera-PardoLaboratorio de Química Aplicada y Sustentable (LabQAS), Departamento de Química, Universidad del Bío-Bío, Avenida Collao 1202, Concepcion 4051381, Chile.
Leandro OrtizInstituto de Ciencias Químicas, Facultad de Ciencias, Universidad Austral de Chile, Valdivia 5110566, Chile.ORCID 0000-0002-8521-1469
Antoni CaminsDepartament de Farmacologia, Toxicologia i Química Terapèutica, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona (UB), Av. de Joan XXIII, 27-31, 08028 Barcelona, Spain.ORCID 0000-0002-1229-5956
Miren EttchetoDepartament de Farmacologia, Toxicologia i Química Terapèutica, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona (UB), Av. de Joan XXIII, 27-31, 08028 Barcelona, Spain.ORCID 0000-0002-4301-7297
Bernd SchmidtInstitut für Chemie, Universität Potsdam, Karl-Liebknecht-Str. 24-25, D-14476 Potsdam, Germany.ORCID 0000-0002-0224-6069
Vaderament-A Nchiozem-NgnitedemInstitut für Chemie, Universität Potsdam, Karl-Liebknecht-Str. 24-25, D-14476 Potsdam, Germany.ORCID 0000-0001-8337-9260
Cristian PazLaboratory of Natural Products & Drug Discovery, Center CEBIM, Department of Basic Sciences, Faculty of Medicine, Universidad de La Frontera, Temuco 4780000, Chile.ORCID 0000-0002-4668-4984

Funding

Agencia Nacional de Investigación y Desarrollo 1220831
6 · The paper itself

Abstract

Neurodegenerative diseases are characterized by a progressive process of degeneration and neuronal death in the nervous system, with neuroinflammation being one of the main factors contributing to the progression of these diseases.

Indexed as

ElaeocarpaceaeIndole AlkaloidsMicrogliaNF-kappa BAnti-Inflammatory AgentsCell LineHumansLipopolysaccharidesPlant ExtractsSignal TransductionAnti-Inflammatory AgentsIndole AlkaloidsLipopolysaccharidesNF-kappa BPlant ExtractsAristotelia chilensismicroglial cell HMC-3NF-κBquinoline alkaloid

Identifiers

PMID40141065
PMCPMC11942453

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.