Evidence map›Paper›PMID 40141122›Full record

ArticleInternational journal of molecular sciences2025

Bilirubin Metabolism Does Not Influence Serum Bile Acid Profiles According to LC-MS: A Human Case-Control Study.

Tamara Christina Stelzer, Ralf Krüger, Paola Gloria Ferrario, Christine Mölzer, Marlies Wallner, Rodrig Marculescu, Daniel Doberer, Andrew Cameron Bulmer, Karl-Heinz Wagner

Abstract read
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In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tamara Christina StelzerDepartment of Nutritional Sciences, University of Vienna, 1090 Vienna, Austria.
Ralf KrügerDepartment of Physiology and Biochemistry of Nutrition, Max Rubner-Institut, Federal Research Institute of Nutrition and Food, 76131 Karlsruhe, Germany.ORCID 0000-0003-1904-8621
Paola Gloria FerrarioDepartment of Physiology and Biochemistry of Nutrition, Max Rubner-Institut, Federal Research Institute of Nutrition and Food, 76131 Karlsruhe, Germany.ORCID 0000-0003-1769-6799
Christine MölzerDepartment of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Vienna General Hospital, Währinger Gürtel 18-20, 1090 Vienna, Austria.ORCID 0000-0002-8015-7774
Marlies WallnerInstitute of Dietetics and Nutrition, University of Applied Sciences FH JOANNEUM, 8010 Graz, Austria.ORCID 0000-0001-7527-8697
Rodrig MarculescuDepartment of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-1772-6695
Daniel DobererVienna Health Care Group, Department of Respiratory and Critical Care Medicine, Klinik Floridsdorf, Bruenner Straße 68, 1210 Vienna, Austria.
Andrew Cameron BulmerSchool of Pharmacy and Medical Sciences, Griffith University, Southport, QLD 4215, Australia.
Karl-Heinz WagnerDepartment of Nutritional Sciences, University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-1683-7265

Funding

FWF Austrian Science Fund P 32303
6 · The paper itself

Abstract

In addition to their role in lipid absorption, bile acids (BAs) are also known for several relevant (endocrine) activities including contributing to the regulation of energy homeostasis and some non-communicable diseases (NCDs). Furthermore, moderately elevated unconjugated bilirubin levels, as observed in Gilbert's syndrome (GS), may protect against NCDs. We therefore hypothesized that the BA profile in GS subjects differs from that of normo-bilirubinemic individuals. To test this, we performed a human case-control study, in which GS (

Indexed as

Bile Acids and SaltsBilirubinGilbert DiseaseAdultCase-Control StudiesChromatography, LiquidFemaleHumansLiquid Chromatography-Mass SpectrometryMaleMass SpectrometryMiddle AgedBile Acids and SaltsBilirubinbile acidsbilirubinhyperbilirubinemia

Identifiers

PMID40141122
PMCPMC11942131

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.