Evidence map›Paper›PMID 40141263›Full record

ArticleInternational journal of molecular sciences2025

Sex Differences in a Novel Mouse Model of Spinocerebellar Ataxia Type 1 (SCA1).

Adem Selimovic, Kaelin Sbrocco, Gourango Talukdar, Adri McCall, Stephen Gilliat, Ying Zhang, Marija Cvetanovic

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adem SelimovicDepartment of Neuroscience, University of Minnesota, 2101 6th Street SE, Minneapolis, MN 55455, USA.ORCID 0000-0003-0334-2033
Kaelin SbroccoGraduate Medical Sciences-Anatomy & Neurobiology, Boston University, Boston, MA 02118, USA.
Gourango TalukdarDepartment of Neuroscience, University of Minnesota, 2101 6th Street SE, Minneapolis, MN 55455, USA.ORCID 0000-0002-8988-6682
Adri McCallDepartment of Neuroscience, University of Minnesota, 2101 6th Street SE, Minneapolis, MN 55455, USA.
Stephen GilliatDepartment of Pharmacology, Yale School of Medicine, Yale University, New Haven, CT 06511, USA.ORCID 0000-0002-8952-6417
Ying ZhangDepartment of Neuroscience, University of Minnesota, 2101 6th Street SE, Minneapolis, MN 55455, USA.ORCID 0000-0003-3764-7329
Marija CvetanovicDepartment of Neuroscience, University of Minnesota, 2101 6th Street SE, Minneapolis, MN 55455, USA.

Funding

Etiology of cognitive decline in Spinocerebellar ataxia type 1R01NS109077 · NINDS · UNIVERSITY OF MINNESOTA · PI Marija Cvetanovic, TIMOTHY J EBNER · 2020 to 2026
$2.4M
Astrocyte dysfunction in Spinocerebellar ataxia type 1 (SCA1)R01NS134916 · NINDS · UNIVERSITY OF MINNESOTA · PI Marija Cvetanovic · 2024 to 2026
$1.4M
Cerebellar Nuclei Dysfunction in Spinocerebellar Ataxia Type 1R21NS136962 · NINDS · UNIVERSITY OF MINNESOTA · PI CVETANOVIC, MARIJA · 2024 to 2024
$424k
NIH HHS R01NS109077 (NINDS NIH HHS R01 NS109077NINDS NIH HHS R01 NS134916NINDS NIH HHS R21 NS136962
6 · The paper itself

Abstract

Spinocerebellar ataxia type 1 (SCA1) is a rare autosomal dominant inherited neurodegenerative disease caused by the expansion of glutamine (Q)-encoding CAG repeats in the gene

Indexed as

Ataxin-1Sex CharacteristicsSpinocerebellar AtaxiasAnimalsCerebellumDisease Models, AnimalFemaleHumansMaleMiceMice, TransgenicAtaxin-1Atxn1 protein, mouseastrocytescognitive deficitsmicrogliamotor deficitsneurodegenerationPurkinje cell pathologySCA1transcriptomics

Identifiers

PMID40141263
PMCPMC11942590

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.