Evidence map›Paper›PMID 40141288›Full record

ArticleInternational journal of molecular sciences2025

Human Brain Endothelial Cell-Derived Extracellular Vesicles Reduce

Luiz Fernando Cardoso Garcia, Victoria Cruz Cavalari, Pryscilla Fanini Wowk, Letusa Albrecht

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luiz Fernando Cardoso GarciaLaboratório de Pesquisa em Apicomplexa, Instituto Carlos Chagas, Fundação Oswaldo Cruz (FIOCRUZ-PR), Curitiba 81350-010, Brazil.ORCID 0000-0002-9616-0927
Victoria Cruz CavalariLaboratório de Pesquisa em Apicomplexa, Instituto Carlos Chagas, Fundação Oswaldo Cruz (FIOCRUZ-PR), Curitiba 81350-010, Brazil.ORCID 0000-0002-0232-7328
Pryscilla Fanini WowkGrupo de Imunologia Molecular, Celular e Inteligência Artificial, Instituto Carlos Chagas, Fundação Oswaldo Cruz (FIOCRUZ-PR), Curitiba 81350-010, Brazil.ORCID 0000-0002-8976-2647
Letusa AlbrechtLaboratório de Pesquisa em Apicomplexa, Instituto Carlos Chagas, Fundação Oswaldo Cruz (FIOCRUZ-PR), Curitiba 81350-010, Brazil.ORCID 0000-0001-6406-2057

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 442377/2019-3Fundação Oswaldo Cruz ICC-008-FIO-21-2-15
6 · The paper itself

Abstract

The endothelial layer, formed by endothelial cells, performs crucial functions in maintaining homeostasis. The endothelial integrity and function might be compromised due to various causes, including infection by

Indexed as

BrainEndothelial CellsExtracellular VesiclesHuman Umbilical Vein Endothelial CellsToxoplasmaToxoplasmosisHumansendothelial dysfunctionextracellular vesicleshost–pathogen interactioninfection modulationToxoplasma gondii

Identifiers

PMID40141288
PMCPMC11942338

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.