Evidence map›Paper›PMID 40142101›Full record

ReviewMolecules (Basel, Switzerland)2025

Analytical Strategies for Green Extraction, Characterization, and Bioactive Evaluation of Polyphenols, Tocopherols, Carotenoids, and Fatty Acids in Agri-Food Bio-Residues.

David Vicente-Zurdo, Esther Gómez-Mejía, Sonia Morante-Zarcero, Noelia Rosales-Conrado, Isabel Sierra

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Myricetin Nanofibers as Amorphous Delivery System.Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Review
  8. Quantitative Analysis of Polyphenols inMolecules (Basel, Switzerland) · 2026
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Foods (Basel, Switzerland) · 2025
    Article
  16. Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David Vicente-ZurdoDepartamento de Tecnología Química y Ambiental, Escuela Superior de Ciencias Experimentales y Tecnología (E.S.C.E.T), Universidad Rey Juan Carlos, C/Tulipán s/n, 28933 Móstoles, Spain.ORCID 0000-0001-8946-2858
Esther Gómez-MejíaDepartamento de Química Analítica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Av Complutense s/n, 28040 Madrid, Spain.ORCID 0000-0002-0786-7999
Sonia Morante-ZarceroDepartamento de Tecnología Química y Ambiental, Escuela Superior de Ciencias Experimentales y Tecnología (E.S.C.E.T), Universidad Rey Juan Carlos, C/Tulipán s/n, 28933 Móstoles, Spain.ORCID 0000-0001-6448-2385
Noelia Rosales-ConradoDepartamento de Química Analítica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Av Complutense s/n, 28040 Madrid, Spain.ORCID 0000-0002-7984-8340
Isabel SierraDepartamento de Tecnología Química y Ambiental, Escuela Superior de Ciencias Experimentales y Tecnología (E.S.C.E.T), Universidad Rey Juan Carlos, C/Tulipán s/n, 28933 Móstoles, Spain.ORCID 0000-0003-2091-6772

Funding

Ministry of Science, Innovation and Universities, the State Research Agency and the European Regional Development Fund (MCIN/AEI/10.13039/501100011033/FEDER, UE PID2022-137278OB-I00Ministry of Science, Innovation and Universities, the State Research Agency and the European Regional Development Fund (MCIN/AEI/10.13039/501100011033/FEDER, UE PID2023-149424OB-I00
6 · The paper itself

Abstract

Recent advancements in analytical strategies have enabled the efficient extraction and characterization of bioactive compounds from agri-food bio-residues, emphasizing green chemistry and circular economy principles. This review highlights the valorization of several agri-food bio-residues for the extraction of high-value-added bioactive compounds, particularly polyphenols, tocopherols, carotenoids, and fatty acids, as a biorefinery approach. To this end, the adoption of environmentally friendly extraction technologies is essential to improve performance, reduce energy consumption, and minimize costs. This study therefore examines emerging methodologies such as supercritical fluid extraction, pressurized liquid extraction, pulsed electric fields, and matrix solid-phase dispersion, highlighting their advantages and limitations. Additionally, the chemical characterization of these bioactive compounds is explored through spectrophotometric and high-resolution chromatographic techniques, crucial for their accurate identification and quantification. This is complemented by an analysis of bioactivity assays evaluating antioxidant, antimicrobial, anticancer, neuroprotective, and anti-inflammatory properties, with a focus on their applications in the food, pharmaceutical, and cosmetic industries. However, the analytical control of toxic compounds, such as alkaloids, in these bio-residues is undoubtedly needed. Ultimately, this approach not only promotes sustainability but also contributes to the development of eco-friendly solutions in various industries.

Indexed as

CarotenoidsFatty AcidsGreen Chemistry TechnologyPolyphenolsTocopherolsAntioxidantsHumansAntioxidantsCarotenoidsFatty AcidsPolyphenolsTocopherolsagri-food bio-residuesanalytical chemistrybioactive compoundscarotenoidscharacterizationcircular economyfatty acidsgreen extractionpolyphenolstocopherols

Identifiers

PMID40142101
PMCPMC11944699

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.