Evidence map›Paper›PMID 40142455›Full record

ArticleMicroorganisms2025

Host-Mediated Antimicrobial Effects and NLRP3 Inflammasome Modulation by Caulerpin and Its Derivatives in Macrophage Models of Mycobacterial Infections.

Maria Gabriella S Sidrônio, Maria Eugênia G Freitas, Daniel W A Magalhães, Deyse C M Carvalho, Vinícius A B Gonçalves, Ana Caroline M de Queiroz Oliveira, Gisela C Paulino, Gabriela C Borges, Rafaelle L Ribeiro, Natália Ferreira de Sousa and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Maria Gabriella S SidrônioPostgraduate Program in Development and Technological Innovation in Medicines, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.
Maria Eugênia G FreitasLaboratory of Biotechnology in Microorganisms, Biotechnology Center, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.
Daniel W A MagalhãesLaboratory of Immunobiotechnology, Biotechnology Center, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.ORCID 0000-0003-2198-1867
Deyse C M CarvalhoLaboratory of Immunobiotechnology, Biotechnology Center, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.ORCID 0000-0002-6987-262X
Vinícius A B GonçalvesDepartment of Cell and Molecular Biology, Biotechnology Center, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.
Ana Caroline M de Queiroz OliveiraFaculty of Dentistry, Unipê, Centro Universitário-Cruzeiro do Sul Educacional, João Pessoa 58053-000, PB, Brazil.
Gisela C PaulinoLaboratory of Biotechnology in Microorganisms, Biotechnology Center, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.
Gabriela C BorgesLaboratory of Biotechnology in Microorganisms, Biotechnology Center, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.
Rafaelle L RibeiroLaboratory of Biotechnology in Microorganisms, Biotechnology Center, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.
Natália Ferreira de SousaPostgraduate Program in Natural and Synthetic Bioactive Products, Department of Pharmaceutical Sciences, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.ORCID 0000-0001-7131-6414
Marcus T ScottiPostgraduate Program in Natural and Synthetic Bioactive Products, Department of Pharmaceutical Sciences, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.ORCID 0000-0003-4863-8057
Demétrius A M de AraújoPostgraduate Program in Biotechnology (Renorbio), Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.ORCID 0000-0001-7320-7203
Francisco Jaime B Mendonça-JuniorLaboratory of Synthesis and Drug Delivery, Department of Biological Sciences, State University of Paraíba, João Pessoa 58071-160, PB, Brazil.ORCID 0000-0003-3588-833X
Kristerson R de Luna FreireDepartment of Cell and Molecular Biology, Biotechnology Center, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.
Sandra Rodrigues-MascarenhasLaboratory of Immunobiotechnology, Biotechnology Center, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.ORCID 0000-0003-4192-7382
Bárbara Viviana de O SantosPostgraduate Program in Development and Technological Innovation in Medicines, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.
Valnês S Rodrigues-JuniorPostgraduate Program in Natural and Synthetic Bioactive Products, Department of Pharmaceutical Sciences, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.ORCID 0000-0002-4849-2249

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caulerpin, a bis-indole alkaloid isolated from

Indexed as

anti-inflammatorycaulerpindrug developmenthost-directed therapytoxicitytuberculosis

Identifiers

PMID40142455
PMCPMC11944515

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.