Evidence map›Paper›PMID 40142825›Full record

ReviewJournal of clinical medicine2025

Predicting New-Onset Atrial Fibrillation in Hypertrophic Cardiomyopathy: A Review.

Marco Maria Dicorato, Paolo Basile, Maria Ludovica Naccarati, Maria Cristina Carella, Ilaria Dentamaro, Alessio Falagario, Sebastiano Cicco, Cinzia Forleo, Andrea Igoren Guaricci, Marco Matteo Ciccone and 1 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marco Maria DicoratoInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", Polyclinic University Hospital, 70124 Bari, Italy.ORCID 0009-0008-4865-2522
Paolo BasileInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", Polyclinic University Hospital, 70124 Bari, Italy.ORCID 0000-0002-2327-7585
Maria Ludovica NaccaratiInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", Polyclinic University Hospital, 70124 Bari, Italy.
Maria Cristina CarellaInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", Polyclinic University Hospital, 70124 Bari, Italy.
Ilaria DentamaroInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", Polyclinic University Hospital, 70124 Bari, Italy.
Alessio FalagarioInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", Polyclinic University Hospital, 70124 Bari, Italy.ORCID 0009-0009-3403-4210
Sebastiano CiccoInternal Medicine Unit "Guido Baccelli"-Arterial Hypertension Unit "Anna Maria Pirrelli", Department of Precision and Regenerative Medicine and Jonic Area (DiMePReJ), University of Bari "Aldo Moro", Polyclinic University Hospital, 70124 Bari, Italy.ORCID 0000-0002-1980-5728
Cinzia ForleoInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", Polyclinic University Hospital, 70124 Bari, Italy.ORCID 0000-0002-9452-4037
Andrea Igoren GuaricciInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", Polyclinic University Hospital, 70124 Bari, Italy.ORCID 0000-0001-7133-4401
Marco Matteo CicconeInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", Polyclinic University Hospital, 70124 Bari, Italy.
Vincenzo Ezio SantobuonoInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", Polyclinic University Hospital, 70124 Bari, Italy.ORCID 0000-0002-8746-729X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertrophic cardiomyopathy (HCM) is a condition characterized by left ventricular hypertrophy, with physiopathological remodeling that predisposes patients to atrial fibrillation (AF). The electrocardiogram is a basic diagnostic tool for evaluating heart electrical activity. Key electrocardiographic features that correlate with AF onset are P-wave duration, P-wave dispersion, and electromechanical delay in left atrium (LA). Clinical markers, including age, body mass index, New York Heart Association functional class, and heart failure symptoms, are also strong predictors of AF in HCM. Risk scores have been created using multiple variables to better predict AF development. Increasing knowledge of genetic subsets in HCM and cardiovascular pathology in general has provided novel insight in this context. Structural and mechanical LA remodeling, including fibrosis, altered LA function, and changes in atrial size, further contribute to AF risk prediction. Cardiovascular magnetic resonance (CMR) and echocardiographic measures provide accurate information about atrial structure and function. Machine learning models are increasingly being utilized to refine risk prediction, incorporating a wide range of variables. This review highlights the multifaceted approach required to understand and predict AF development in HCM. Such an approach is imperative to enhance prognostic accuracy and improve the quality of life of these patients. Further research is necessary to refine patient outcomes and develop customized management strategies for HCM-associated AF.

Indexed as

atrial cardiomyopathyatrial fibrillation (AF)cardiovascular magnetic resonance (CMR)echocardiographyelectrocardiogram (ECG)geneticsheart failurehypertrophic cardiomyopathy (HCM)left atrial remodelingmachine learning

Identifiers

PMID40142825
PMCPMC11942920

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.