Evidence map›Paper›PMID 40143028›Full record

ArticlePharmaceutics2025

Therapeutic Efficacy of Small Extracellular Vesicles Loaded with ROCK Inhibitor in Parkinson's Disease.

Candy Carbajal, Myosotys Rodriguez, Florida Owens, Nicole Stone, Dileepkumar Veeragoni, Rebecca Z Fan, Kim Tieu, Nazira El-Hage

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Candy CarbajalDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.ORCID 0009-0002-4909-5242
Myosotys RodriguezDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.ORCID 0000-0002-3925-9023
Florida OwensDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.ORCID 0000-0003-1303-7809
Nicole StoneDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.ORCID 0009-0006-4274-9951
Dileepkumar VeeragoniDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.
Rebecca Z FanDepartment of Environmental Health Sciences, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL 33199, USA.ORCID 0000-0002-9091-1830
Kim TieuDepartment of Environmental Health Sciences, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL 33199, USA.ORCID 0000-0001-6606-4371
Nazira El-HageDepartment of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.

Funding

Toxicant-induced neurotoxicity mediated by glia-neuron and gene-environment interactions in Parkinson's diseaseR35ES030523 · NIEHS · FLORIDA INTERNATIONAL UNIVERSITY · PI KIM TIEU · 2019 to 2026
$6.7M
Title: Pharmacokinetic, pharmacodynamic , and toxicological interactions among Opioids and CabotegravirR01DA057145 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI Shilpa J Buch, NAZIRA EL-HAGE · 2022 to 2026
$2.5M
Function of astrocytes autophagy in brain homeostasis and opioid-induced maladaptive behavior and addiction, in the context of HIVR01DA057884 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI NAZIRA EL-HAGE, Jay P. McLaughlin · 2023 to 2026
$1.4M
NIDA NIH HHS R01 DA057145NIDA NIH HHS R01 DA057884NIEHS NIH HHS R35 ES030523NIH HHS R01DA057145NIH HHS R01DA057884
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

drug delivery systemextracellular vesiclesintranasal deliveryParkinson’s diseaseROCK

Identifiers

PMID40143028
PMCPMC11944340

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.