Evidence map›Paper›PMID 40143149›Full record

ReviewPharmaceuticals (Basel, Switzerland)2025

Bioactive Substances and Skin Health: An Integrative Review from a Pharmacy and Nutrition Perspective.

Rafael Jesús Giménez Martínez, Francisco Rivas García, Joan Carles March Cerdá, Ángela Hernández-Ruíz, Martha Irene González Castro, María-Isabel Valverde-Merino, Felipe José Huertas Camarasa, Fuensanta Lloris Meseguer, Margarita López-Viota Gallardo

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rafael Jesús Giménez MartínezDepartment of Nutrition and Bromatology, School of Pharmacy, University of Granada, 18071 Granada, Spain.
Francisco Rivas GarcíaMunicipal Health and Consumer Unit, Guadix City Council, 18500 Guadix, Spain.ORCID 0000-0002-4488-8262
Joan Carles March CerdáAndalusian School of Public Health, 18011 Granada, Spain.
Ángela Hernández-RuízDepartment of Physiotherapy, Nutrition and Sports Sciences, Faculty of Health Sciences, Universidad Europea de Valencia, Paseo de la Alameda 7, 46010 Valencia, Spain.ORCID 0000-0001-5957-0372
Martha Irene González CastroSchool of Nursing and Nutrition, Autonomous University of Chihuahua, Campus 2, Chihuahua 31125, Mexico.
María-Isabel Valverde-MerinoPharmaceutical Care Research Group, School of Pharmacy, University of Granada, 18071 Granada, Spain.ORCID 0000-0001-8875-1551
Felipe José Huertas CamarasaAdvanced Chemistry Laboratory, University of Almeria, 04120 Almería, Spain.
Fuensanta Lloris MeseguerDepartment of Educational Development and Vocational Training, Andalusian Government, 18016 Granada, Spain.
Margarita López-Viota GallardoDepartment of Pharmacy and Pharmaceutical Technology, School of Pharmacy, University of Granada, 18011 Granada, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The skin is one of the largest and most important organs of our body. There are numerous factors that are related to skin health, including lifestyle factors, nutrition, or skin care. Bioactive substances from plant and marine extracts play a key role in skin health. The aim of this research was to compile the main evidence on skin and bioactive substances. An integrative review was performed, reporting the main findings according to PRISMA (2020). Thirteen search equations were developed. After the applications of the equations and the process of screening and selection of articles, 95 references were compiled. The main results related to bioactive compounds were classified into food-derived components, nutraceuticals, symbiotics, active substances of marine origin, and substances from plant extracts). There are several factors that indicate that the use of bioactive compounds are interesting for skin health, highlighting some dietary nutrients, substances obtained from plant extracts and metabolites of marine origin that, showing anti-inflammatory and antimicrobial effects, are related to the improvement of some skin conditions or are active principles for cosmetics.

Indexed as

bioactive substancescosmeticsnutritionpharmacyskin

Identifiers

PMID40143149
PMCPMC11944704

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.