Evidence map›Paper›PMID 40143288›Full record

ArticleViruses2025

Identification of Early Biomarkers of Mortality in COVID-19 Hospitalized Patients: A LASSO-Based Cox and Logistic Approach.

Anna Maria Fratta Pasini, Chiara Stranieri, Edoardo Giuseppe Di Leo, Lorenzo Bertolone, Antonino Aparo, Fabiana Busti, Annalisa Castagna, Alice Vianello, Fabio Chesini, Simonetta Friso and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Anna Maria Fratta PasiniDepartment of Medicine, Section of Internal Medicine D, University of Verona, Policlinico G.B. Rossi, Piazzale L.A. Scuro 10, 37134 Verona, Italy.ORCID 0000-0001-7661-7785
Chiara StranieriDepartment of Medicine, Section of Internal Medicine D, University of Verona, Policlinico G.B. Rossi, Piazzale L.A. Scuro 10, 37134 Verona, Italy.
Edoardo Giuseppe Di LeoDepartment of Medicine, Section of Internal Medicine D, University of Verona, Policlinico G.B. Rossi, Piazzale L.A. Scuro 10, 37134 Verona, Italy.ORCID 0009-0003-2742-1358
Lorenzo BertoloneDepartment of Medicine, Section of Internal Medicine D, University of Verona, Policlinico G.B. Rossi, Piazzale L.A. Scuro 10, 37134 Verona, Italy.
Antonino AparoInterdepartmental Laboratory of Medical Research, Research Center LURM, University of Verona, 37134 Verona, Italy.ORCID 0000-0002-4107-6680
Fabiana BustiDepartment of Medicine, Section of Internal Medicine D, University of Verona, Policlinico G.B. Rossi, Piazzale L.A. Scuro 10, 37134 Verona, Italy.
Annalisa CastagnaDepartment of Medicine, Section of Internal Medicine B, University of Verona, Policlinico G.B. Rossi, Piazzale L.A. Scuro 10, 37134 Verona, Italy.ORCID 0000-0002-4650-0823
Alice VianelloDepartment of Medicine, Section of Internal Medicine D, University of Verona, Policlinico G.B. Rossi, Piazzale L.A. Scuro 10, 37134 Verona, Italy.ORCID 0000-0002-2428-4760
Fabio ChesiniDepartment of Medicine, Section of Internal Medicine D, University of Verona, Policlinico G.B. Rossi, Piazzale L.A. Scuro 10, 37134 Verona, Italy.ORCID 0009-0001-5770-8160
Simonetta FrisoDepartment of Medicine, Section of Internal Medicine B, University of Verona, Policlinico G.B. Rossi, Piazzale L.A. Scuro 10, 37134 Verona, Italy.ORCID 0000-0002-9606-6711
Domenico GirelliDepartment of Medicine, Section of Internal Medicine D, University of Verona, Policlinico G.B. Rossi, Piazzale L.A. Scuro 10, 37134 Verona, Italy.ORCID 0000-0001-9684-1899
Luciano CominaciniDepartment of Medicine, Section of Internal Medicine D, University of Verona, Policlinico G.B. Rossi, Piazzale L.A. Scuro 10, 37134 Verona, Italy.

Funding

University of Verona No grant number
6 · The paper itself

Abstract

This study aimed to identify possible early biomarkers of mortality among clinical and biochemical parameters, iron metabolism parameters, and cytokines detected within 24 h from admission in hospitalized COVID-19 patients. We enrolled 80 hospitalized patients (40 survivors and 40 non-survivors) with COVID-19 pneumonia and acute respiratory failure. The median time from the onset of COVID-19 symptoms to hospital admission was lower in non-survivors than survivors (

Indexed as

BiomarkersCOVID-19AdultAgedCytokinesFemaleHospitalizationHumansInterleukin-10L-Lactate DehydrogenaseLogistic ModelsMaleMiddle AgedPrognosisProportional Hazards ModelsRespiratory InsufficiencyBiomarkersCytokinesInterleukin-10L-Lactate DehydrogenaseCOVID-19early biomarkersinterleukin-10lactate dehydrogenase

Identifiers

PMID40143288
PMCPMC11946718

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.