Evidence map›Paper›PMID 40143295›Full record

ReviewViruses2025

Relationship Between Human Papilloma Virus and Upper Gastrointestinal Cancers.

Ömer Vefik Özozan, Hikmet Pehlevan-Özel, Veli Vural, Tolga Dinç

Abstract readReview
In one paragraph

Review in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ömer Vefik ÖzozanÖmer Özozan Private Clinic, Kadıköy, 34744 İstanbul, Türkiye.
Hikmet Pehlevan-ÖzelDepartment of General Surgery, Ankara Bilkent City Hospital, 06800 Ankara, Türkiye.ORCID 0000-0002-9146-3742
Veli VuralDepartment of General Surgery, Akdeniz University, 07070 Antalya, Türkiye.
Tolga DinçDepartment of General Surgery, Ankara Bilkent City Hospital, 06800 Ankara, Türkiye.ORCID 0000-0003-3772-7468

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human papillomavirus (HPV) is an oncogenic DNA virus that is the most commonly transmitted sexually transmitted virus. There is substantial evidence that HPV is associated with different types of cancer. While the majority of studies have concentrated on urogenital system cancers and head and neck cancers, the relationship between HPV and gastrointestinal system cancers, particularly esophageal cancers, has also been the subject of investigation. Given that HPV is a disease that can be prevented through vaccination and treated with antiviral agents, identifying the types of cancers associated with the pathogen may inform the treatment of these cancers. This comprehensive review examines the relationship between HPV and cancers of the upper gastrointestinal tract, highlighting the oncogenic mechanisms of the virus and its reported prevalence. A deeper understanding of HPV's association with cancer is relevant to the further development of cancer therapies.

Indexed as

Gastrointestinal NeoplasmsPapillomaviridaePapillomavirus InfectionsEsophageal NeoplasmsHuman Papillomavirus VirusesHumansesophagus cancergastric cancerHPVhuman papillomavirus

Identifiers

PMID40143295
PMCPMC11946559

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.