Evidence map›Paper›PMID 40143312›Full record

ArticleViruses2025

A Spatiotemporal Analysis of a High-Resolution Molecular Network Reveals Shifts of HIV-1 Transmission Hotspots in Guangzhou, China.

Huanchang Yan, Yifan Lu, Shunming Li, Hao Wu, Jingyang Hu, Yefei Luo, Qingmei Li, Lingxuan Lai, Weiping Huang, Jing Gu and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Huanchang YanSchool of Public Health and Management, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Yifan LuSchool of Public Health and Management, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Shunming LiDepartment of AIDS Control and Prevention, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.
Hao WuDepartment of AIDS Control and Prevention, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.
Jingyang HuSchool of Medical Information Engineering, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Yefei LuoDepartment of AIDS Control and Prevention, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.ORCID 0000-0003-0912-976X
Qingmei LiDepartment of AIDS Control and Prevention, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.
Lingxuan LaiSchool of Public Health and Management, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Weiping HuangDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou 510515, China.
Jing GuDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.ORCID 0000-0001-5436-2339
Lijun MaSchool of Public Health and Management, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Yuantao HaoPeking University Center for Public Health and Epidemic Preparedness & Response, Beijing 100191, China.
Zhigang HanDepartment of AIDS Control and Prevention, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.
Xin-Lin ChenSchool of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Yu LiuSchool of Public Health and Management, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.ORCID 0000-0002-5263-9610

Funding

Guangdong Basic and Applied Basic Research Foundation 2021A1515011591Guangdong Medical Science and Technology Research Foundation A2023393Guangzhou Medical Science and Technology Grant 2023B03J1259, 2025A03J3540 and 2025A03J3698Humanities and Social Sciences Cultivation Project of Guangzhou University of Chinese Medicine 2024ZXPY22National Key Research and Development Program of China 2023YFC3503002
6 · The paper itself

Abstract

backgroundHigh-resolution and longitudinal HIV molecular surveillance can inform the evolving hotspots to tailor regionally focused control strategies.

methodsHIV-1

resultsOf the 2469 PLWH, 55.5% resided in the central area. Clustering rates showed no significant differences across areas (44.5%, 40.6% vs. 45.7%;

conclusionsDespite most PLWH residing in the central area, the outer suburban area emerged as the hotspot, requiring interventions towards both intra- and inter-area transmission.

Indexed as

Disease HotspotHIV-1HIV InfectionsAdultChinaFemaleGenotypeHumansMaleMiddle AgedMolecular EpidemiologyPhylogenypol Gene Products, Human Immunodeficiency VirusSpatio-Temporal Analysispol Gene Products, Human Immunodeficiency Virushuman immunodeficiency virusmolecular transmission networkspatiotemporal analysis

Identifiers

PMID40143312
PMCPMC11945462

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.